Interferon

[hbsag]

Hi there. Im on my 6 months of treatment of Interferon 5 miu 3x a week. Just like to know if after my treatment and my Viral Load is undetectable, do i need to continue? What will happen if i stop?

[catmon1204]

    Hi , I'm Hbag Positive / Hbeag Neg (Viral Hepa B).My doctor advice me to take Lumivudine (Zeffix 100mg) for 6mos.
     I can't start my medications because i' m worried about if it help for me or not, as i've read from this forum one say : "Lamivudine is no longer considered a suitable first line therapy?. It is true?  OR when i take it ,what will happen if i stop?
    Please help me and give me some advice if i will continue this kind of medicine or u can give me a good one...

[zellyf]

Different people have different reactions to interferon.  Some do quite well and continue to work.  Lamivudine is no longer considered a suitable first line therapy.  

[skylanator]

I feel soooo bad for you.  I don't know interferon didn't work for me.  I was born with HBV, and took interferon when I was 9 or so.  It made me horribly sick, every night I took it.  I had fevers of 104 and 105, I was always soo nauseated.  Worst feeling ever by far.  EVER.  Good luck, I hope it helps you.  There are other therapies available, like lumivudine, and there have beeen experimental studies shown with both medicines, but you'll have to look it up.  

[cajim]

>>>If you do reach your goal with one course of treatment

I mean "If you do not reach your goal with one course of treatment"

Sorry.

[cajim]

"The advantage of interferon is that you can stop treatment in some patients. And certainly with 12 months treatment about 15-20 percent of patients would have a sustained response with two years treatment."

>>>do i need to continue? What will happen if i stop?

I think with interferon treatment if you reach your goal, the response stays.  If you do reach your goal with one course of treatment, I have read that some papers say that the longer the treatment the more patients will reach their goals.

Best.