6 weeks post tx problems

[alijee]

im facing low Blood pressure, extreme head spinning these day. im still on escitalopram 5mg (half doz) since mid of tx. One month ago i tried to tapper off AD but i felt extreme head spinning and IBS diarrhoea. Then i started AD again alongwith probiotics (Actiflora) sachete hence, spinning and IBS problem was solved.
Now i m facing head spining problem and diarrhoea without tappering off the AD. i feel alway lazzy, no energy, sleepy. Week 3-4 post tx were very good. Now even i can ride on bicycle daily which is comparatively better than during tx.
Plz can any body tell me what is this? and why im feeling head spinning, low BP and loose stool even im taking AD regularly??? Is there anything wrong? Should i go to Doc or not take it serious? Is it post tx sx or something else???

ali

4 weeks post tx labs were as under:-

Hgb        15.0 g/dl       14-17
ALT        35.0 u/l         10-43
PLT        224.00/cm     >50
TLC        5400


WBC      5.4x10*3/ul
RBC       5.09x10*6/ul
HCT       47.5%
MCV      93.3fL
MCH      29.5 pg
MCHC    31.6 g/dl


LYM%   32.9%
MXD%    18.5%
NEUT%   48.6 %

LYM#     1.8X10*3 /ul
MXD#     1.0X10*3 /ul
NEUT#   2.6x10*3 /ul

RDW  12.0%

PDW     13.6 fL
MPV      10.5 fL
P-LCR    28.6 %

[mkp13]

Yeah, go to the doc.  But I remember having a similar thing.  It wasn't as severe as yours, but I felt very lightheaded at about the same time you did.  I'm now almost 4 months post-treatment.  It's been several weeks since I've felt lightheaded, so at least for me it went away.  I think it lasted a week or two at varying intensities.

Hope yours goes away too.

[alijee]

Thank u very much for for great information

[fretboard]

That would be troubling to have these things pop up post tx or at any time for that matter.  In the clip I leave below it talks about a study that was done on patients 8 and 12 wks post tx and it basically verified that after that small of a time frame things were still out of whack.  No big surprise there to anyone, I'm sure.  The dizzyness is the thing that stands out the most as having low blood pressure can be attributed to other things.  You should also determine why the sudden low blood pressure as I didn't mean to minimize, if of course you weren't anemic going in to tx.  I almost always have low blood presure but it's not tx related in my case.  Hopefully you and your doctor will come to a conclusion soon about your health.  good luck  


[Attention abnormalities in patients with chronic hepatitis C after pegylated interferon alpha and ribavirin treatment]
[Article in Polish]

Pawełczyk T, Białkowska J, Jabłkowski M, Pawełczyk A, Strzelecki D, Rabe-Jabłonska J, Dworniak D.

Uniwersytet Medyczny w Łodzi, Klinika Zaburzeń Afektywnych i Psychotycznych. ***@****

THE AIM OF THE STUDY: To (a) describe the influence of peg-IFNalpha 2a and 2b on attention processes and (b) to assess whether attention abnormalities induced by peg-IFNalpha/RBW resolve 8 weeks after treatment discontinuation in chronic hepatitis C patients. MATERIAL AND METHODS: 26 chronic hepatitis C patients treated with peg-IFNalpha2a (n=18) or 2b (n=8) and RBV were enrolled in the study. Attention processes were tested three times: before the beginning (t=0), after 12 weeks of medication (t=1) and 8 weeks after treatment discontinuation (t=2). Attention was assessed with Brickenkamp d2 test and the results were compared in groups of patients treated with different kinds of peg-IFNalpha. RESULTS: The two kinds of peg-IFNalpha did not differ significantly regarding the influence on attention processes. 8 weeks after treatment discontinuation (t=2) there was observed a significant decrease all aspects of attention measured by d2 test, i.e. work accuracy, speed of processing and ability to focus attention comparing with t=0 and t=1. CONCLUSIONS: Peg-IFNalpha/RBW therapy is connected with a decrease in attention processes performance and the two kinds of peg-interferon alpha (2a and 2b) may exert a similar influence. Attention dysfunction did not resolve 8 weeks after treatment discontinuation and may be the irreversible effect of the dorso-lateral prefrontal cortex or anterior cingulate cortex damage.

[Trinity4]

Yeah, go to the doctor.  Nobody here can diagnose your post EOT problems.

Seems like you had a lot of side effects and problems during tx so it might be related.