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1084115 tn?1385228589

thinking about quit treatment already

hello dear community,

i realy start to thinking about stop treatment.
im just in week 2 but i feel so terrible that i cant imagine go on for
so many more weeks.
my main problem is the nausea,the doc gave me zofran im taking 3 times 4 mg, wich helps a little but i still hardly cant eat anything .
my weight is dropping and i was very thin already before i started treatment.
but when i stop what next?
i know in some time i will die, so this fear is the only reason is still didnt quit.
sometimes i think,it could be worse and maybe iam acting like a sissy.
its just so hard to see iam soon just of bones and skin.

regards
28 Responses
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Avatar universal
Tuff it out at least until you get your first viral load results.  Believe me you don't want to go the route where you reach cirrhosis and possibly transplant.
Helpful - 0
Avatar universal
Wow you are light for your height especially for a man. I don't think that alone would determine if your body can handle it as many lighter people have treated. If there is a medical condition or some other problem contributing to your being thin pre-tx then I suppose that could be an issue. Something to discuss with your doctor though.

I lost 25 lbs (about 11kg) in my first 8-10 weeks of tx. I wasn't thin to begin with but still this was about 13% of my pre tx weight.

Good luck with whatever you decide to do,
-Dave
Helpful - 0
1084115 tn?1385228589
forgot to write that I'm 180 cm height and my weight is now only 52 kg.I lost 3 kg in this week,this what makes ne worry If my body even can handle that all.
Helpful - 0
1084115 tn?1385228589
I very appreciate all your posts.today morning the nausea wasn't too bad but later came back full again.
the zofrans seem not work even with 20 mg a day.the only thing that's working a bit is ginger tea from the Asia shop.
well I decided to go on sure till Monday and then discuss this with my doc,but he's not in he's office so u have to talk with his represantiv doc.
I hope so much its getting better.

again thanks for all tips and opinions.feels good that here are some poeple who know what I'm going thru.
Helpful - 0
Avatar universal
I will echo what others have suggested:  talk to your doctor about the anti-nausea meds, drink lots of water, try Ensure, raw ginger, ginger candies (found in Asian markets),and ginger tea.  When my husband, who is currently in his 3rd treatment for Hep C, isolates himself and doesn't talk with me about how he is feeling, I get frustrated and upset, because then I don't know how I might be able to help him.  Talk to your doctor about your side effects, but I agree with others above, now is the time to treat if you can push through the side effects.  If you wait for the new medications, your liver damage may progress, which could reduce your chances for success or even make a future treatment impossible.
Advocate1955
Helpful - 0
1814148 tn?1332485798
I'm so sorry to hear your struggle with nausea. Definitely go to the doctor asap and see what else he can offer.

There are a few different classifications of antiemetics. Which one is chosen depends on which trigger zone in the brain is causing the nausea. I'm not going to get into the pharmacokinetics of it but you are needing something that targets the chemorecptors. Zofran doesn't work for everyone and another medication should be added to provide you relief from this distress. Nausea is telling the body that the stomach needs to empty. Domperidone and Metacloperamide (Maxeran) and meds that help empty the stomach faster. They should be taken 3-4 times a day prior to meals or drink as a preventative measure. Chlorpromazine (Stemetil) and Haloperidol (Haldol) are usually the next line of meds used, they bind with specifc receptors that trigger nausea. They can be taken preventively or as needed.

It's not uncommon to use a few different meds to treat chronic nausea. I hope you can talk to your doctor soon and get your symptoms under control. Things will get better once you bring out the 'big guns' lol. I have been dealing with nausea for awhile now and haven't even started treatment yet. Dehydration make nausea worse and I feel so much better when I take sips of ice water and sports drinks throughout the day. The key is ice cold. I have also been getting accupuncture. It worked great for my anxiety induced insomnia and I'm now starting it for nausea. I have noticed significant improvement after my first treatment.

I read stories here and as a nurse I have seen treatment in action. Sure it has made me fearful and want to run and hide. I'm 38 too and this gives us the reserve to make it through the physical crap. There is a huge emotional aspect to living with any chronic condition, which we tend to ignore. I have been to counsellors and support groups. I'm so happy to have found this forum of people dedicated to wellness. The members have more knowledge than most doctors, not to mention what their lived experiences can teach me.  

We hold the pen that writes our life story. When it's a matter of life over limb, so to speak, I choose life. I pray that you do too. Peace :o)
Helpful - 0
789911 tn?1368636783
Whenever you do feel like you can eat, lots of calories and fat .whatever you can stand, but a potato chip wont keep much meat on your bones.  try ensure or boost.  That will keep nutrition in your body.  Sometimes all I could eat/drink  was some olvalteen  with milk
Helpful - 0
665963 tn?1360723554
I can't offer any better advice than has already been offered here, but, please know,  everybody who has treated understands what you're going thru.  You are not alone in this. This forum is an amazing resource.
Helpful - 0
Avatar universal
Hang in there rexx. talk to your wife about how you feel, scream and cry and try to keep going if you can. Treatment will have it's ups and downs.

Many people use anti depressants or anti anxiety medication during tx also which is not a sign of weakness in my opinion. And as Hector said who cares anyway. This isn't a contest to see how much a person can take and you don't need to apologize that it's getting to you physically or mentally.

These meds are rough. use whatever tools you have at your disposal to rid yourself of this disease.
-Dave
Helpful - 0
1856494 tn?1340542614
One of the most inspiring and amazing threads ever!!!!
Helpful - 0
789911 tn?1368636783
I would get nauseated , light headed dizzy, pale, staggering,  and super nauseated about 30 minutes before I would take the inc.  My body knew it was coming.  I wouldnt let anyone else in the house use the bathroom in my bedroom.  I had wipes, hand towels , a stool to sit on and a small blanket within reach, and bottled water.   It was war!  But after I got it out, I alway felt much better,  It was an everyday occurrence for most of the time I was on it.  I have been off of it for quite a while and have only thrown up once.   I am starting week 33/48 tonight!   Hang in there,   See if you can get a viral load test done, you might already be und.  get lots of rescue meds.  I remember popping those nausea pillls like they were tic tacs.  At least that is what it seemed like!
Helpful - 0
419309 tn?1326503291
Treatment can be physically, emotionally, as well as mentally challenging, and it's normal to have ups and downs.  Just as folks here want to support you, I'm sure your wife would rather you shared your feelings rather than hide them from her, and crying is an expression of what you're going through, so I'm sure your wife will understand.  If you find treatment is making you more depressed than what is typical for you, you should speak with your physician; treatment can be psychologically debilitating and some folks benefit from anti-depressants in order to help maintain the course of treatment.

I echo can-do-man and Hector:  keep seeking options; talk to your doc about increasing your Zofran if necessary, or perhaps another anti-emetic might work better for you; keep ginger or lemon drops or bittersweet chocolate on hand (just a few things that worked for my husband); eat as frequently as you can, even if it means small meals often, and supplement with protein shakes or milkshakes to increase your protein and calorie intake and weight.  

Being a stage 3 or 4, treatment is probably more likely to be successful and better tolerated now than at a later time... hang in there.  Take it one pill, one symptom, one shot at a time, and don't just don't give up for today... hopefully that will carry you each day into another tomorrow.
Helpful - 0
Avatar universal
Sorry to see you are having such a tough time. Others have already said all the sensible things like get to the bottom of this with your doctor.

You said that you don't want your wife to see you crying. I want to pass on  something that someone said to me once when I was struggling and keeping it all to myself. When you don't tell people close to you that you need help and let them see you pain you deny them the chance to help you. People like to help their friends and loved ones. I opened up a bit and you know what she was right.

I bet if once in a while you let your wife see you how you feel it will actually be a relief. She must know that you feel bad already. Let her in! There is a greater strength in being open about vulnerability and it can bring people closer.

One foot in front of the other. One day at a time. You have options.
Helpful - 0
1494170 tn?1361750860
One more thing: about being a sissy
Even the last 2 rounds I did of the double dose stuff left me feeling like this too but that is the nature of this treatment.
Please try and get a hold on the nausea and try and continue on this treatment ONE DAY AT A TIME!!!!

Good Luck
Helpful - 0
Avatar universal
I think that maybe something is wrong with my body because my appetite was already before tx bad,started all this summer and didn't get better.had a gastroscopy and many blood checks but the didn't find something
****
Yes.  Treatment can make everything worse.  Maybe you and doc can look for the primary cause of the problem.  Is there any chance of depression?  Sometimes that affects the appetite.  No matter what, it is not the end of the world like Hector said.  
Helpful - 0
1084115 tn?1385228589
Thanks a lot.
till now I did not vomit.just deep nausea and gaging.
my hope is that it gets a bit better after a while. the 48 weeks of soc have been a walk in the park compared to this round so far.
Helpful - 0
1084115 tn?1385228589
thank you so much for your effort you put in this post.
that's why I wrote about being a sissy above.it could be much worse and maybe I really have to be thankfully for still have the option to treat.
I will try it with more zofran look what happen.
Helpful - 0
190885 tn?1333025891
i was so sick the first few weeks of tx with incivek...it got much better for me after week 3...i still gaged a few times a day..when i did i quickly took zofran...4 mil...most times even though i didn't feel at all like eating if i could eat anything it helped a lot....i would hang in there...get blood work every week...keep a close eye on things...make sure you talk with your doctor about rescue drugs and when they have you take them...like at what hgb# would they start procrit???...if your doing triple tx it does work well but can be tough...stay on the forum for support ..that will help a lot....don't miss any incivek doses.....good luck...billy
Helpful - 0
1494170 tn?1361750860
Hi rexx,
So sorry to hear this is making you so sick but that is kind of what this stuff does to us.
I " REALLY " hope you can HANG IN THERE man cause the alternative su*** a lot worse then the sx's

Try not to quit Bro if at all possible!!!

Gene
Helpful - 0
446474 tn?1446347682
Rex I am sorry you are having a tough time. But no matter what happens...it is not the end of the world not even close.

The normal dosage of zofran in the US is 2x 8mg per day. Or 16 mg per day. You are talking 12 mg per day. Maybe you need more? Ask you doctor.

If the drug is not working for you it probably means that the treatment is not the cause of your nausea. Zofran is a powerful and effective drug. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting. It is used to prevent nausea and vomiting caused by cancer chemotherapy, radiation therapy, and surgery. I just had chemo treatment on Monday and without the IV Zofran, there is no way to get through treatment without vomiting while undergoing the chemo and post treatment for days afterward. So I have personal experience knowing how it would stop me from vomiting within seconds of its application by IV.

You don't remember you mentioning vomiting. Do you vomit or is it only the feeling of nausea? Nausea can be caused by many conditions including physiological ones. From what I remember you had nausea before even starting treatment. Treatment is a big commitment of time and energy and should not be started until all other health issues can be resolved if possible. It is like trying to fight with one arm tied behind you. Very few people if any need to start treatment now vs in a few months when they are prepared to start treatment. Liver disease is a slow moving disease. It doesn't change over night.

"i know in some time i will die, so this fear is the only reason is still didnt quit.sometimes i think,it could be worse and maybe iam acting like a sissy. its just so hard to see iam soon just of bones and skin. "

Okay lets have a little reality check here.
1. Your liver disease is not stage 4, cirrhosis so you still have time to treat and maybe with drugs that will be available in the next 3-4 years. Numerous tests that you have had confirm this diagnosis. 190,000 platelet count, no varices, etc.
2. The fact is the persons with advanced liver disease are the only ones with the symptoms of nausea and you are very far from End-Stage Liver Disease. Don't believe me ask your doctor. If he knows anything about liver disease he will tell you the same. Stage 3 liver disease and End-Stage Liver Disease are like the difference between having a "cold" and having pneumonia. Two different animals.
"its just so hard to see iam soon just of bones and skin."
3. This claim is so over exaggerated as to be either comical or scary. Someone who is skin and bones. Do you look like a concentration camp survivor? Can everyone see every bone in your body? Do you have bruises all over your body? Is your abdomen so bloated that you look like your are pregnant with triplets? Can you no longer take care of your self? Even the basics like going to the bathroom? Are you hospitalized 24/7? I don't believe so. You do have the energy to post on Medhelp.I appear to somehow get to your doctors office. Well people that are truly End-Stage with MELD score in the 30s are experiencing the complications and symptoms I mention above. So please get some perspective on your situation. It will be better for you and all involved. I know it is hard but you should feel lucky for all the options you still have for stopping your liver disease progression. Some of us are beyond having any options but a liver transplant. If you have to stop treatment all is not lost. Educate yourself about hepatitis C and liver disease. It can be difficult but there are diseases even worse that have no cures. No options. Be grateful you don't have one of them. The world is not black and white.

4. "i know in some time i will die" I hate to be the bearer of bad news but  we are all gonna die one day. When and how you die sometimes can be of our own choosing. Be smart about it and don't get all depressed and throw in the towel. Believe me I would love to be in your position and so would most people I know with advanced cirrhosis who are waiting for transplants. Don't squander the options you still have by being angry cause life ain't fair. Is it fair for all those kids that have fatal diseases and all the poor people that happen to be born in countries that have no health services? Of course not. It is not their fault. Believe me we have more things going for us than you can ever imagine. So in time pick yourself up and get back in the fight more informed and with the will to take on hepatitis C. Keep fighting and believe you can win. Other partial responders are getting cured so it is possible and it is now more possible then ever.
5. You are not a wimp or sissy. We all are. So what? Who can judge you? No one. So who cares what anyone else thinks? We all do the best we can under the circumstances.
Myself, I get down and feel hopeless at times. Yes I feel like I've wasted so much of my life on nonsense. What can I do? I can't change the past. What happened, happened. Time to grow up and be a man (whatever that means) and take responsibility for my life and possible death. If I don't who will? Trust me I hate needles. You would think after all this time I would get used to it. No way. How many times have I cried while having MRIs, CT scans and just thinking about how my life has bit by bit disappeared. No career. Social life takes too much energy.
There is no answer anywhere. You have to find that inside yourself. Find the will to live despite the obstacles and limitations. The only heroes are the one we never hear of. That are fighting the good fight every day against the odds. I ain't one of them. If you are. More power to ya. I don't worry about being a "sissy". Most people are when they face their own death. It is easy to have an opinion when it is an abstract concept. All logical and stuff. But from my point of view all the hero (men in white hats) nonsense is some writer's fantasy. Don't waste your time worrying about not being worthy. It ain't real anyway, in my opinion.

Hang in there> Things are no as bleak as they appear.
Take care.
Hector
Helpful - 0
Avatar universal
Since your already late stage 3 or maybe even 4 now and only age 38 you really need to make a full court effort here, please set down and talk with your doctor, have you tried things like smoothies, shakes, even ensure.Also Zofran doesn't work for all, my liver doctor recommends phenergan for severe nausea.

Wishing you the best
Helpful - 0
1815939 tn?1377991799
I had the same problem. Even the thought of food made me nauseated and I got where all I was eating was Greek yogurt and eggnog and a few crackers and bread. I finally asked for Zofran after I started vomiting. At first the doctor gave me only 4 mg and not even enough for every 8 hours. After 3 days I got 8 mg twice a day. Finally I had had it and asked for 8 mg 3 times a day. It is true, the 4 mg and the 8 mg twice a day did help, but not enough. The 8 mg three times a day is working well as long as I take it every 8 hours without fail and take it about an hour before I plan to eat and take pills. Try to get Zofran 8 mg three times a day and see if that will do the trick. If not, the doc needs to find a med that works.

Some things do get better with time and the symptoms come and go (although the nausea and bloating just stayed until I got Zofran). I finally made it to 12 weeks and have only 2 1/2 days left of Incivek. I don't feel great, but I rest and take the Zofran and the Tylenol and the Benadryl and the hydrocortisone cream and the meds for the flaming butt and I am feeling positive and optimistic (Not great, but optimisitc that soon I will be rid of this virus. I am UND as of week 8.)

So try to get a high enough dose that will work and get rid of the nausea and I think you will feel so much better. I know I did. It was like night and day.

I wish you the best.
Helpful - 0
1084115 tn?1385228589
well thanks a lot so far,as for other options I think I have no time to wait for new drugs as I am already f3 or even f4.this is all so scary and I don't want my wife is see my crying.
Helpful - 0
1747881 tn?1546175878
Nausea was the biggest problem I had with the incivek as well but after finishing the incivek the nausea went away,  I have no personal expirience with zofran but have seen that some are taking 8 mg at a time, I would check with my doc and see if this was ok. Incivek is only for 12 wks and just try to take it one day at a time. I told myself on many occasions it's just 1 dose and that seemed to help. Hang in there and I hope you can get it under control.
Helpful - 0
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