Boceprevir Trial Started

[Rockerforlife]

Hi all,just did my first shot and and 3 Ribas in the Doctors office about 3 hours ago...juts waiting for the "shake rattle and roll" to hit me...BTW i like the palm pilot they give you to keep track of the the meds ...once a day you log on the machine and enter your data....make sit easier to NOT miss your meds...good thinking by someone out there in big pharma land...this thing is even wireless and has a camera and a key board...looks jus like a black berry...pretty wild...anywho...i do 3 more shots and then i go in for the BOC meds and pray i get the real deal...have a beautiful weekend to you all

r.s

[Isobella]

Yay for you!  Congrats on jumping back in.   Hope the weekend brings light and sunny sides =)

Here's to you getting the real deal.....all the best,

Izzy

[comeagain]

Welcome aboard, are you supposed to do 48 weeks or 24w ?
Yea we really hopes you get the real stuff'.

Good Gods bessings.

ca

[Rockerforlife]

Depends on the  trial arm i will be  randomly chosen to be in at wk 4...there are 3 different arms ...i will post the info in a sec

[nygirl7]

Good luck Rocker I hope this time is the charm, I really do.  Enough is enough.

[Rockerforlife]

Arm 1: Placebo Comparator
PegIntron (PEG) + Ribavirin (RBV) (weight-based dosing [WBD]) for 4 weeks followed by boceprevir placebo + PEG + RBV (WBD) for 44 weeks with 24 weeks post-treatment follow-up.


Arm 2: Experimental
Subjects in Arm 2 will be assigned either a 36-week or 48-week course of therapy based on their HCV-RNA status at Treatment Week 8.

PEG + RBV (WBD) for 4 weeks followed by boceprevir + PEG + RBV (WBD) for 32 weeks, then:

36-week regimen: Subjects who have undetectable HCV-RNA at Treatment Week 8 discontinue treatment and enter 36 weeks of post treatment follow-up.
48-week regimen: Subjects who have detectable HCV-RNA at Treatment Week 8 are assigned an additional 12 weeks of therapy, followed by 24 weeks of post treatment follow-up. Placebo replaces boceprevir for the remaining 12 weeks of therapy, and this switch will occur in a blinded fashion.



Arm 3: Experimental
PEG + RBV (WBD) for 4 weeks followed by boceprevir + PEG + RBV (WBD) for 44 weeks with 24 weeks post-treatment follow-up.




http://clinicaltrials.gov/ct2/show/NCT00708500?recr=open&cond=%22Digestive+System+Diseases%22&rank=29

[can-do-man]

Best of luck to you guy, i am suppose to start next friday.

cando

[Rockerforlife]

Thanks you guys....and gals...i will keep you all up todate on my progress....i can feel the shot already...its just like getting the flu....no big deal...the worse part of tx is the Riba i think...maybe my gogi berries and coconut oil will keep the ribs monster at bay.

[Rockerforlife]

ive been reading gogi berries are excellent for fatty liver....just wanted  to throm that in before i forget...I LOVE THOSE berries

[frijole]

rocker
Sounds great.  I too hope this is the one.  That palm pilot deal is pretty neat.  A camera?  What do they want -- to see you actually swallowing the pills and taking the shot?

cando -- you are on right now.  Hi guy.  You MUST email fishdoc and tell her! She was asking about you this week.  She said she would even get back on MH once you started!!!!!  Cando - I am just thrilled for you.
frijole

[meakea]

Welcome to the treatment amusement park ride.  :)  I wish you the best!!

[Bill1028]

Good luck Rocker!  I’m going in next Thursday for my start.  I don’t get why they want to give the first shot in the office.  I always did my shots on Friday nights and took a Tylenol PM and slept like a baby.

[copyman]

good luck rocker, you are right behind me. I started the telaprevir study 3 weeks ago. KILL the dragon!

[can-do-man]

Thanks gal, fishdoc back on at medhelp??? That makes doing tx worth it. That gal is more crazy then i am.:)

[Rockerforlife]

I did not have to do the first shot in the office...i just thought it would be wise...who knows if the shot gun delivery system had changed or not...im doing the redi-pen ..just wanted to make sure...also had a palm pilot instruction course...LOL..seems like a waste of money to me just to keep track of my neds...this thing cost at least 300 -500 bucks...guess im worth it

[Rockerforlife]

This palm pilot is freakin me out...it even has bluetooth and a phone   and the camera...i can even access the internet...AMAZING

[sugarplum49]

i am + for hep c the viral load is 177000 stage 2 grade 1  what does this mean ? Thanks so much ! God Bless

[Bill1028]

This will be my first time taking pegintron (hopefully my last).  If anyone has treated with pegintron and pegasys, how did you find pegintron compared to pegasys?

Thanks Rocker.  How was the redipen?  I’m a baby and had my wife give all the shots except for one.  Between all of the crying and shaking, I don’t even know if I got any of the injection.  Besides that, I’m not to be trusted with sharp objects.

[Rockerforlife]

What does this mean?....im  the same as you...stage 2...moderate damage to your liver..half way mark if you will...your VL looks  low in relative terms...my base load was 5 million starting this time ...whats your genetype ?...1..1A...2   OR 3?

[Rockerforlife]

I ACTUALLY love using the redi-pen...as opposed to the regular syringes...those things gives me the sahkes just lookn at them...never mine using them...the redi-pen is easy as pie...if you cant do the redi-pen...you have a problem...LOL...if you can stick the tail on the donkey...without the blind fold of course...your in


BTW....the shot is coming on now...it hurts my fingers to type...and you say your the baby?

[TeeVee36]

Congratulations on starting your tx!!

Is this a second time around for you?  I see that you have been a member since '05.

Anyway, take it easy and keep us posted.

So glad your journey has begun!

TV

[Rockerforlife]

I did the IDEAL STUDY back in 2006 and the monster reared its ugly head again after one month...im in another trial now...its the Boceprevir...i finally spelled that damn word right...

[can-do-man]

I will be getting that palm thingy next week, after tx do we get to keep them or do we have to steal them??? :)

[Fl_Gator]

Welcome to the club...I hope all goes well for you. Please keep us posted.

I did shot # 22 this morning. I should have waited another hour or two...I'm starting to feel it now and it's too early...the kids are coming over...I'm not cooking...they're getting pizza...dam'it....not cooking.  

[Marcia2202]

BADSS Bro', you kick a§§ big time!

I'm so happy you finally started! I'll be right here if you need me.

I think I'll get a bowl of goji berries and put them nest to my bed to nibble on them.


Hugs, Marcia