Gilead Trial with Sofosbuvir & GS-5816

[mdudley]

Gilead Sciences:  Twelve week Phase 2 trial of sofosbuvir + GS-5816 (without ribavirin or interferon) for genotypes 1, 2, and 3 treatment-naïve.

The Protocol Number:  GS-US-342-0102
Clinical Trial Number:  NCT01858766

Anyone else in the Gilead 12-week trial with sofosbuvir & GS-5816 (without ribavirin or interferon)?  The initial enrollment was 140 patients and I would like to connect with or hear from anyone else who may be in these trials.  Thanks!

[Stronglady14]

Still undetected, liver enzymes in the teens. I have 17 more pills to take. And right now I am suffering from a horrible sore throat. Went to a clinic today to test for strep throat and don't have it. Already had scarlet fever as a child don't want it again. I pretty much had every childhood disease , my Mom was a nurse.
Wanted for that test that takes a month is gonna seem awfully long.

[caz77777]

How is everyone doing? I have 12 pills left. I feel very rough today after a trip to the clinic yesterday, it's a long day out. No news, my enzymes have dropped a tiny bit to 42 (ALT from 47) and 32 (AST from 44). They keep saying this is no big deal as they were in the normal range already but I was so hoping for them to be in the 20s. I will just have to wait. I am sure I have the real drug, far too many good and bad effects...better digestion but feel spaced and exhausted, it's different from the hep C exhaustion though. I had hives come up on my wrist last night and today...weird...
Hope everyone is ok!

[Stronglady14]

I just read on forum that weaning off the med can be tougher then taking it. I hope that isn't the case with this trial medicine. I have 24 days to go and have noticed hair loss and my skin getting really dry now. Also my nails are pretty much shot. I would do this again if I had to the side effects to me a not bad. My goal for this year is to keep a healthy diet and please hope to quit smoking. I will not take the medicine to quit I already take enough meds . Have severe spinal issues due to a very bad accident so I live on some heavy pain meds. I'm hoping I can somehow help heal my liver while still on these meds. Unfortunatly I will never be without severe pain.  Also hoping that pain Dr. will be able to at least make it so I can drive again, at least local driving. I hope everyone has a good year just remember your body is your temple and you only get one. If you abuse it in any form it tends to get even.

[OMECO]

Probably I just have the flu. All my muscles and joins hurt more then usually

[OMECO]

Headaches every day now. Feeling exhausted every now and then, specifically at the end of the day. But the first four weeks are almost done and I 'm still very happy to know that I have the real stuff.

[Micahblue]

Just wanted to wish everyone a Blessed Christmas and happy as well healthy New Year! I have 2 more pills to take (Sovaldi & GS5816) then I get my blood tested in 1 month, then 2 months out. I am sure I am on a placebo....but I am thrilled to be ending this part of the experiment for Gilead. Glad we are taking a 3 month break, wiill be happy to start the REAL drug in March hopefully. Prayers to all for good health and to beat this draining disease!