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317787 tn?1473358451

Incivek blocks prozac - severe anxiety is with me

Hello this is not a question more an attempt to help anyone else going though SEVERE Anxiety, if you can't sleep or stop talking or don't feel like eating.
I started the Prozac 4 to 6 weeks before Incivek so it would be in my system to help with depression and anxiety
I just called the Specialty Pharmacist at Aetna and she said my problem is that the Incivek has been blocking my Prozac and that is why I am driving all of you crazy with pleas for help
I apologize from the bottom of my heart.  I hope you can understand me wanting to share what the pharmacy told me.  I mean no offense, I am still on treatment week 14 of 24 I was UND at 4 8 10 12 weeks
I would like to thank all the people that have PM'd me with support and suggestions, at least now I know what to do.  I am in a little bit of trouble but I will be ok and I will be SVR!
You all are right, you have to fight and you have to be proactive and you can not give up, even when people te4ll you, oh that is not a side effect of Incivek, it's not but it blocked my prozac per pharmacy.  I am now having panic attacks
Thank you all so very much. My HGB is now 9.8 and the doc says I am stable, no rescue drugs.  My next call may be to a blood specialist,
I wish you all the very best as always.  The Incivek is still in my system so I now do not know how much Prozac to take or how much was blocked for 12 weeks.
Dee1956
Best Answer
Avatar universal
You are not driving anyone crazy. We are all different and no medication will effect everyone in the same way (as you know) AND the health professionals and doctors learn as more people take the treatment meds and the other meds that waylay some of the sides. I took a generic for zoloft while on treatment to prevent depression and I think it did a good job. That said however, one thing I did not share with anyone here is that I feel that I had an emotional  "meltdown" around 8-10 weeks in to the treatment. This had absolutely nothing to do with my stopping incivek- the only reason I stopped was on doctor's order due to severe rash. I did not discuss the meltdown with him either. I worked as a senior manager and fortunately was slated to take a few days off work for vacation around that time. I am so glad for that coincidence. It also happpened that I had a ton of vacation time available (never missed work and didn't take other time off). I have been off work since that time and able to use vacation time. I was starting to lose it when I went on that vacation but unfortunately my perspective on what was going on with me left me along with everything else and I could not stop what was happening or control it. I was able to isolate myself enough at work due to my job (before I went out) so that the stuff that did happen at work, I managed to hide. No one at work knew of my treatment and they still don't. There were times that I either laughed way, way, way, too much or sat in my office in the dark and just cried. I just could not keep it together. I do have a terminally ill family member and I think people assumed something was up with that when I looked funny coming out of my office. I am fine now but the craziness didn't stop until weeks after I stopped the incivek. I don't know that it was caused by the incivek but I think so and I know from the rash that it takes a while for incivek to get out of your system. It was still worth taking all of the meds to get rid of the hep c but it does seem strange, doesn't it? Now that I am a lot more "sane" I know that something was really wrong at that time. I also could not sleep.

Remember that one of the reasons drs began routinely prescribing the ADs was because some people were depressed to the point of harming themselves. Can the drugs alone or in combination cause other emotional or behavioral issues? It doesn't seem like much of a stretch. The doctors should continue to prescribe the ADs but maybe they will find out that some are better than others and will be able to get this treatment process fine tuned. Sorry to go on so long but this is an important topic. Thank you for bringing it up.  Even though I am repeating myself I must say again that it was still worth taking the meds to get rid of the hep c and I am so happy that the tx is working for you, Dee.  I hope everything else gets better for you!
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Avatar universal
Hi Dee...you sound much better. We are all rooting for you .Every one has made some excellent points and no-one is in the least upset with you. :0)
Will
Helpful - 0
317787 tn?1473358451
Thank you so much for the information.  I have een told that I am stable and do not need rescue drugs but have been asured, the first blood work that shows a problem they will help me
I think I may be on their radaor now LOL
Especially since I was his first Incivek patient, he is a Hepatologist and he is experiences with Riba and Peg however if Vertex did not mention possible interactions what could he do?  Don't I sound better?  I feel better and to every person who has responded, you have helped me and kept me going and my eye is on the prize..It has been a rough road since Nov 28th however I believe I have gotten some good advice and a doctors support..
You are right about the blood work though a regular doc would not understand the numbers, maybe a hemotologist - blood specialist?
Thank you again I am really out of breath just typing, it is so weird
Dee
Helpful - 0
317787 tn?1473358451
Thank you so very much for sharing, now that the doctor has called and verified that I should have had my xanax modified as the Incivek would make it a double dose.  Also the Prozac that I used in the last trial very well was able to work 36 hours a week; was abruptly stopped which is dangerous.
I appreciate your feedback  I am doing a little better today.  I thought that if the drug was approved in May and I did not start till Sept and they had studied for 10 years someone would know.  However saying that, before I found out the doc just kept saying that it was the Incivek, that the drug was very hard and I was just going to have to bear up which I was desperately trying.  I have been told I have done very well
Bless you again for your reswponse, I am very vulnerable, insecure and today is shot day woo hoo
Helpful - 0
317787 tn?1473358451
Last night when I wrote wht happened I was upset and when I finished typing was just too tired to retype. Sorry for the caps, I know it means a person is yelling or crazy I was neither.  Well, maybe angry but I apologize
Thank you for your support, I slept 5 hours last night and today is shot day whoo hoo!!!!!!  I am UND
Love to all of you
Dee
Helpful - 0
1654058 tn?1407159066
Well I'll join the sleepless talk. I never could take Ads. I have taken 1/2 ambien or 1/2 Xanax to sleep, but use it sparingly. Not al all most nights cause I can fall asleep, just up at midnight n it's too late to take something n get up at 5:30 for work.
I will say that you're such a sweet lady. Everyone on here are all just trying to muddle through in their own way. We analyze everything. And we should. Its a fight to enjoy our lives here on this planet. As an outside objective viewpoint reading these posts? I hear love n concern. Not a person here wants to see you or anyone else suffer needlessly. Any one of is would fight for you and with you to get some relief.
Speaking for myself - I know I'm a lil crazy right now. My thots are good some days n messy 10 minutes later. This roller coaster is the pits. . Grab every minute of peace you can find. Please know you're not alone. I glory in ur spunk n determination. You're taking care of Dee. Just do that. Everything is going to turn out fine in the long run. Thats my truth that keeps me going n I'm sticking w it. Xoxo Karen :)
Helpful - 0
Avatar universal
Dee, I'm not going to comment on the Prozac / anxiety meds as I don't know enough about the interactions to make a comment.  I was reading through your symptoms though and I was thinking..."she sounds like me when my thyroid went hyperactive" and I kept reading...and then I got to this:

" for my thyroid TSH which went from 3 d.35 down to 1 which means my thyroid meds were being increased "

That's hyperactive thyroid, Dee.  Did your doctor say anything about that?  That doesn't mean you need your thyroid meds increased, it means you're hyperactive and making TOO MUCH thyroid hormone.    Your TSH is dropping.  Mine dropped to .02 when they caught it.  My hands were shaking and I couldn't focus as well, my balance was a little off.  I was sleeping about two hours a night.  Felt like an airplane ready to take off all the time.  My hep doctor asked me to hold out my hands when I told him how I was feeling and my hands were shaking.  He put me on beta blockers right away until I could get to an endocrinologist.

You might have a whole bunch of things going on at the same time here, Dee.

I'd push for an appointment with your endocrinologist about your thyroid asap.  Call them yourself and tell them your thyroid TSH is at 1 (or is it at .1, Dee?)  Tell them you're not sleeping at all and that your anxiety is heightened.  Tell them you're on interferon and that it can impact auto-immune issues.  I hope you have a good endocrinologist.

I'd also talk to that doctor about getting on procrit asap to bring your HGB up.  Below 10 is the point where most doctors do something about that. I'm not sure what he means by stabilized if you get winded by typing.  I remember those days when it was too tiring to sit at the keyboard and type and needed to lie down.  Please ask that doc about procrit - it takes about 3 weeks to kick in and I wouldn't want to see your hgb to keep dropping.

What week is this now, Dee?

And NOBODY is bothered by your posts or your questions, I know willbb and all of us are concerned on whether you were getting good information and good care, we all want you to get through this and get SVR and everyone is trying to help as best they can.

Hang in there, girlie.  Take it a step at a time, an hour at a time, a day at a time.  You're going to get there.

Trish
Helpful - 0
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