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317787 tn?1473358451

Incivek blocks prozac - severe anxiety is with me

Hello this is not a question more an attempt to help anyone else going though SEVERE Anxiety, if you can't sleep or stop talking or don't feel like eating.
I started the Prozac 4 to 6 weeks before Incivek so it would be in my system to help with depression and anxiety
I just called the Specialty Pharmacist at Aetna and she said my problem is that the Incivek has been blocking my Prozac and that is why I am driving all of you crazy with pleas for help
I apologize from the bottom of my heart.  I hope you can understand me wanting to share what the pharmacy told me.  I mean no offense, I am still on treatment week 14 of 24 I was UND at 4 8 10 12 weeks
I would like to thank all the people that have PM'd me with support and suggestions, at least now I know what to do.  I am in a little bit of trouble but I will be ok and I will be SVR!
You all are right, you have to fight and you have to be proactive and you can not give up, even when people te4ll you, oh that is not a side effect of Incivek, it's not but it blocked my prozac per pharmacy.  I am now having panic attacks
Thank you all so very much. My HGB is now 9.8 and the doc says I am stable, no rescue drugs.  My next call may be to a blood specialist,
I wish you all the very best as always.  The Incivek is still in my system so I now do not know how much Prozac to take or how much was blocked for 12 weeks.
Dee1956
Best Answer
Avatar universal
You are not driving anyone crazy. We are all different and no medication will effect everyone in the same way (as you know) AND the health professionals and doctors learn as more people take the treatment meds and the other meds that waylay some of the sides. I took a generic for zoloft while on treatment to prevent depression and I think it did a good job. That said however, one thing I did not share with anyone here is that I feel that I had an emotional  "meltdown" around 8-10 weeks in to the treatment. This had absolutely nothing to do with my stopping incivek- the only reason I stopped was on doctor's order due to severe rash. I did not discuss the meltdown with him either. I worked as a senior manager and fortunately was slated to take a few days off work for vacation around that time. I am so glad for that coincidence. It also happpened that I had a ton of vacation time available (never missed work and didn't take other time off). I have been off work since that time and able to use vacation time. I was starting to lose it when I went on that vacation but unfortunately my perspective on what was going on with me left me along with everything else and I could not stop what was happening or control it. I was able to isolate myself enough at work due to my job (before I went out) so that the stuff that did happen at work, I managed to hide. No one at work knew of my treatment and they still don't. There were times that I either laughed way, way, way, too much or sat in my office in the dark and just cried. I just could not keep it together. I do have a terminally ill family member and I think people assumed something was up with that when I looked funny coming out of my office. I am fine now but the craziness didn't stop until weeks after I stopped the incivek. I don't know that it was caused by the incivek but I think so and I know from the rash that it takes a while for incivek to get out of your system. It was still worth taking all of the meds to get rid of the hep c but it does seem strange, doesn't it? Now that I am a lot more "sane" I know that something was really wrong at that time. I also could not sleep.

Remember that one of the reasons drs began routinely prescribing the ADs was because some people were depressed to the point of harming themselves. Can the drugs alone or in combination cause other emotional or behavioral issues? It doesn't seem like much of a stretch. The doctors should continue to prescribe the ADs but maybe they will find out that some are better than others and will be able to get this treatment process fine tuned. Sorry to go on so long but this is an important topic. Thank you for bringing it up.  Even though I am repeating myself I must say again that it was still worth taking the meds to get rid of the hep c and I am so happy that the tx is working for you, Dee.  I hope everything else gets better for you!
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163305 tn?1333668571
You have every right to be upset. This is infuriating.

I wish you were here and could go to my hepatologist, He is always so kind, compassionate and willing to work with me.
And I love that he never hesitates to say, ' we don't know." His ego is not his main interest.

Hopefully, you will feel better soon and can move forward.

Good luck,
OH
Helpful - 0
317787 tn?1473358451
After 8 days of severe abrupt withdrawal from my Prozac because Incivek has been blocking absorption, and withdrawal for Xanax because for every xanax I appropriately took the Incivek turned it into 2 doses and for my thyroid TSH which went from 3 d.35 down to 1 which means my thyroid meds were being increased

I just received a call from my top hepatologist and he told me that it is unfortunate that that you are experiencing this problem. We did not realize until yesterday when you called (again and again) that there is a problem and I am not sure what we could have done. I asked why we did not change my prozac, etc., and he said that most of those antidepressants are going to have the same symptoms.  

For all of you like me fight, call your doctors and tell them what you are experiencing. I am feeling withdrawals for the first time in my life.  He never said he was sorry for my pain or mistake in not checking the meds when I called to ask for them to recheck drug interactions.

Please e4xcuse me I am so hurt and upset that no one believed me because it was not written down yet.  Now the Doc has checked with Vertex it is fact.   For all of you who have supported amd comforted me thank you God Bless you and never give up in this fight against Hep C.  It will not happen to every one but it will happen.  I guess the part that gets me is how hwsaid how unfortunate it was that I started treatment so early (Sept 1st)
I love all of you very much
Dee
Helpful - 0
190885 tn?1333025891
dee...i thought it was riba and prozac that could be trouble with some folks...when i have more time i'll try to look up that link someone sent me..hopefully last tx that wasn't a problem for you...good luck....billy
Helpful - 0
Avatar universal
Dee,
You wrote:  * I will not write any more as I can tell some people might be angry with me,*  
I'm sure no one on this forum is angry with you.  I'm sure everyone cares about you and wants you to be well and have relief from the side effects of therapy.  Best wishes for a calm, happy, relaxing day!
Advocate1955
Helpful - 0
1794638 tn?1345155061
Oh Dee, My heart is with you.  I absolutely know what your are talking about.  I have been on Lexa Pro for 10 years and knew in advance that INC might cause Potential  loss of concomitant medication activity.    So the doctor pumped it up a little and increased my ativan to 3 mg a day.  All I can say is that it has been an emotional and physical roller coaster over the last 12 weeks on INC.   I just was not willing to change my AD, because of previous sx and adverse reactions, so I just fought it out.   But I will say that there were times that the anxiety was pretty well kept under control because the INC made me really sleepy, so in the long run it was all good.  
Now on my 4th day post INC and I am starting to see some comeback qualities from my AD, ie:  a little more motivation and energy, but I am still hitting a wall around 4-5PM everyday and the confusion & brain fog sets in along with body aches and pain.   My sleep has been intermittent at night and I am not getting solid sleep until about 3AM-6AM.  
Hang tough girl   Prayers
Helpful - 0
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