It was not this time ... yet ... PSI -7977

[liavera]

Hi, there. Today I went to have a first dose of double INTERF / riba but the  doctors convinced me to compete for a place in study group with PSI-7977. Well .. they advised me it would be better option than starting tx now because I have a chance to succeed. Result: the beginning of the tx was in the middle of the year. Does this attitude was good? I can still change my mind and opt for the conventional tx now ...

Lia

[Advocate1955]

Yes, as I recall you are f3 Lia, so you and your docs do need to take that into consideration as you research the the PSI-7977 trial, the number of months before it starts, and all of the details of the trial (what are the chances of you being on a placebo, how long will the trial last, will you be able to take rescue meds to stay on the Hep C drugs if you become anemic or neutropenic, if it turns out you are on a placebo would you then get the PSI-7977 drug afterward, etc.).
Advocate1955

[liavera]

I hope by then my not increase the degree of fibrosis and I don't get cirrhotic  ... but the doctors know what they do ... I think ...btw, I'll try and wait ... meanwhile enjoying the carnival in Brazil ... no alcohol ...
hugs, my best to all
Lia

[curiouslady1]

I know.  So they are at least going to do the BMS/PSI extension at your site and my site.  There are 4 arms.  Two for naives and two for failures to the triple.  I don't know if all the original sites will be doing the extension.
http://www.dailymarkets.com/stock/2011/11/04/new-12-week-interferon-free-treatment-arms-added-to-all-oral-combination-study-of-psi-7977-and-daclatasvir-bms-790052-for-hcv-genotype-1/

My understanding is that they may be screening now but they won't be starting until March or so because they dont have the drugs out yet.  Ran out I guess.  

[gonnabhepcfree]

My coordinatior told me yesterday that they are going to be starting a new study with our study drugs for geno 1a naive and people who failed triple.  I believe she said another for just four weeks but not 100 percent on that one.  

[curiouslady1]

Can you tell us the name or number of the trial?  Some are listed at clinicaltrials.gov.  

[curiouslady1]

Ah.  I see you found the page.  The trial must be available in your country to participate.  Not all trials have placebos.  Even the ones who have placebos with Hepatitis C, they are given a chance to have treatment after a period of time.