Aa
Aa
A
A
A
Close
225275 tn?1276957893

PLEASE READ THIS AND HELP !!!!

i hope someone can help me. I saw a post the other day about not having a certain protein while on treatment. I think the name was isonone, but I am not sure. All I remember was that it did not let the ribivarin absorb properly. I tried to find it again and I can't find it :-( please someone help me. I am a non responder and I am waiting for the new drugs to come out. I want to make sure that I do everything right this time to reach SVR !!!!!! Thank you so much
11 Responses
Sort by: Helpful Oldest Newest
233616 tn?1312787196
the links given by myself and another member did have peer review and are published and accepted by those who understand the chemistry. Right now they are working on several different trial drugs to try and get the riba to absorb better. The idea of getting riba to absorb better by finding out what is interfering with good absorption is not new, it's why tests were done on bowel tissue, and in human beings to see what blocked or interferred most with absorption amonngst the things people normally eat high proteins with salt were the main culprits.  The person saying there was no peer review didn't evidently look at the evidence or it's peer review.  
Helpful - 0
Avatar universal
This may be related to a query I posted earlier today, in which I said, "I just read that inosine triphosphate pyrophosphatase (ITPA) deficiency is a clear risk factor for early onset of anemia during HCV treatment, necessitating that ribavirin be reduced or discontinued." and asked if there is a test for ITPA.

The only reply said that this is a non issue.  But query whether it's a big issue for those people who can't tolerate ribovirin and thus relapse or don't respond because of their genetic makeup.

BTB

Helpful - 0
225275 tn?1276957893
O.K. , O.K. get it!! be very careful of what you hear without proof. This is why I am on this site, as to get everyones input on things I hear and think might help. We ( or should I say I ) Am looking for everything and anything to help with my treatment to get to SVR.I am so sick of this virus and how it has disturbed my whole life. I am waiting for the new drugs to come out and I have a Very Promising outlook for this time around. They say the new drug is hopefully coming out this summer, but who really knows!!!! I wish that they could give us al the information we so desperatly need for some HOPE !!! I am not looking towards my hair loss again :-( , it took me three years to grow it back !! But this is such alittle sacrafice to be a Survivor of this inflicting virus. I want to THANK each and everyone of you that cared to reply. I pray for all of us to be SURVIVORS !!!! and that they can destroy this virus once and for all. PLEASE< if anyone has any new information I will be so greatful if you send it my way. I have not been on this website for quite awhile. Guess sometimes I try to forget that I have this virus :-( . But reality sets in and I have to take my head out of my A- - And keep on trying to find some new info. GOD BLESS YOU ALL !!!!!!
Helpful - 0
96938 tn?1189799858
After all that condescending instruction you are still confusing bovine with isonine. Or, is it purine? .  Nevermind, I need to go back to make sure it wan't assinine.  
Helpful - 0
179856 tn?1333547362
You know how hard I am rooting for you stalion...I want to see you win the first time so much my fingers and toes hurt from being crossed for so long :D
Helpful - 0
1201433 tn?1328997637
Hi Deb I am a newbie, I have 4 more weeks of tx, what I take away from the people who have posted here, that is if you are geno-1a like I am , you will probably have to treat again. That is why they say 50% clear the virus. I didnot go und at 12 weeks, so I probably have even less than that, My regret is that I have had this since the 70,s and I didnot find out sooner. Some people feel I am being negative, but I am a realist, I prepare for the worst, and if it goes well I am pleasantly surprized! I have recieved more info, from here, so if I have to treat again, I will have some different stratergies. Hopfully if I have to go it again, maybe the new tx will be availble, and tx will be shorter! good luck to you stalion
Helpful - 0
179856 tn?1333547362
NYgirl < Jumping Over the Moon

Yes let the buyer beware is always the correct mantra when something is not studied, proven, peer reviewed and is only someones guess - even if it seems to make sense how do you really know this might not backfire in someway that could prove even more harmful? You dont. Be careful!
Helpful - 0
87972 tn?1322661239
Moooo!
Helpful - 0
87972 tn?1322661239
Moooo!
Helpful - 0
Avatar universal
I hope you realize that thread is speculation with no peer reviewed studies to back it and eliminating protein and salt from your diet doesn't mean a damn thing nor does it move you closer to SVR.  The original poster is not a dietitian, nutritionist or a hepatologist and cannot speak with certainty that her viewpoints are true just as I can't when I say:  

         ***********************************BUYER BEWARE*********************************

I am also a relapser and view that whole concept as utter nonsense but to each his own fancy said the old lady as she kissed the cow.

Trinity

Helpful - 0
148588 tn?1465778809
The 'Isonine Thread'
http://www.medhelp.org/posts/Hepatitis-C/Ribavirin-absorption-fats-and-PURINEs/show/1446708
Good Luck with that and when you understand it, please explain it to me.
Helpful - 0
Have an Answer?

You are reading content posted in the Hepatitis C Community

Top Hepatitis Answerers
317787 tn?1473358451
DC
683231 tn?1467323017
Auburn, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Answer a few simple questions about your Hep C treatment journey.

Those who qualify may receive up to $100 for their time.
Explore More In Our Hep C Learning Center
image description
Learn about this treatable virus.
image description
Getting tested for this viral infection.
image description
3 key steps to getting on treatment.
image description
4 steps to getting on therapy.
image description
What you need to know about Hep C drugs.
image description
How the drugs might affect you.
image description
These tips may up your chances of a cure.
Popular Resources
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.
Condoms are the most effective way to prevent HIV and STDs.
PrEP is used by people with high risk to prevent HIV infection.