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Just done 28 weeks peg, rib, boceprevir. Was RGT naïve had all the best numbers.
Greater than One log drop week 2, greater two log week 4, cleared week 8. Stayed clear until week 12 post treatment.  In the process of finding out about mutations. Any and all comments would be helpful.
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Avatar universal
Did not reach week 12.
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Avatar universal
And just to clarify things, PI's do not CAUSE mutations. They simply create an environment in which only copies of the virus with the particular resistance mutation can SURVIVE and MULTIPLY.

All my best to you leo_rex. I can really understand how frustrating, dissapointing, and heartbreaking it must be to relapse. I know from personal current experience how invested we get in curing ourselves. It's a real letdown to find out we were one of the unlucky ones.

Stay tough.

RBW
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Avatar universal
"Hmmm. Maybe Merck can spin the term  "evidence of mutations" to their benefit. Really crummy as a trial participant to think you have to parse info on a consent. Don't you think?"

Oh believe me, I understand your frustration, and I'm no friend of the way corporate America operates. We both may be in the same boat here shortly.

As I struggle with deciding whether to continue in my study, or stop treating, I constantly have to remind myself that the purpose of the trial is not to cure me, or even to do what's in my best interest as a patient. Rather, their only goal is to complete a drug trial.

As long as they don't commit malpractice, there's nothing I can do.

:-(
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Avatar universal
Don't worry you can hi Jack my thread anytime. I value your input.
I was in the anemia study.
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476246 tn?1418870914
If you don't mind me asking, did you actually reach SVR 12? Or did your 12 weeks post PCR come back positive.

I am asking, cause you would be the first person I heard of that tested negative week 12 post and then relapsed. It has often been mentioned that SVR 12 is as sure as SVR 24 and I would like to verify that.

Hang in there Leo!
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476246 tn?1418870914
I'm so sorry to hear that you relapsed. That sukks real bad!
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