Telaprevir non-responders

[pjhep80]

anyone????

mostly hearing good news but i know its not working for everyone...

[copyman]

I meant for tx naive that got all three drugs, telaprevir, ribavirin & interferon that have posted on this forum. i have read the data and know there are some that got all three drugs and it still did not work. But overall it has shown great results providing you get all three of the real drugs.

[can-do-man]

http://www.natap.org/2008/EASL/EASL_05.htm

[lapis]

So there's no data yet about tx-naive subjects, is there?  Haven't seen it...

[can-do-man]

http://www.hivandhepatitis.com/hep_c/news/2008/061308_c.html

[susan400]

It did not work for me and other group C people who only had the Telaprevir and the Pegasys with NO RIBA.   Since I now have exposure to the Telaprevir, it's hindered my chances considerably for treating in any of the other trials for protease inhibitors, such as Boceprevir.  I tried to see if I could get into that trial and was told that I would not be able to be accepted into any trials that are using protease inhibitors.  So, now I'm left with if anybody will ever consider me for a trial for a non-responder for a polymerase inhibitor.  Or, if I am fortunate enough to have prescription drug insurance that will cover the new drugs when they come out, then I could wait until then.  But, that's a big if.  Most of these new drugs will be very expensive and on an upper Tier with pre-authorizations needed ad nauseum!   I know this from past experience with trying to even get coverage for just the regular interferon/Riba.  When Riba first came out, I was in a late stage trial for the Riba and when it was FDA approved, my doctor wanted to role me over into having my regular insurance pay for it and I was turned down.  Finally, I was able to get it directly through the drug company.  

Susan400

[copyman]

I have been on the forum for 2 yrs and I have never heard of anyone Telaprevir has not worked for. Even people that were pulled off telaprevir early because of rash still SVR'd. Of course there are people it did not wotk for but they have not posted here, unless I missed it or forgot (which is a possibility lately)

[Isobella]

Bumping you up because I'm curious as well =)


Isobella