changed mind....again!

[brianmo]

I have decided to not go with Inc. and do Vic instead (4 week lead in). I start tx on the 22nd so this is a last min. decision. The anxiety I was having  was unbearable. I could not rap my brain around the 60 grams of fat. I don't eat cheese or bread so that didn't help so after a week of anxiety I talked with doctor and we decided to do the other triple therapy. Now I feel better and not spending so much time with list of fat and searching the stores for what I could possibly eat. I know i have to eat with the Reba dose but she said a snack will do. Does not have to be high fat. Its not that I was afraid of putting on weight, it was more of not being able to do it!  What surprises me the small amount of people on this sight who are doing Inc instead of Vic. Either way, I just want to get this started!

[willbb]

Oh look..the centuries old (well since 2001 anyway) argument about fat with Riba again.

"Bioavailability"  means the portion of a dose that reaches circulation.  Higher fat food will slow absorption of most drugs(including Riba)   ..but will not have much effect on "bioavailability"

In the Schering Plough study Riba was given with no regard to food, and concluded because uf uncertainty about effects of food they said it may be prudent to take Riba  "with food"       it said nothing about  "high fat food"

For those of you on Inci..it is mostly moot anyway as I would imagine you are taking the Riba at or about the same time as Inci and the fat is adequate ....for those on Vic   because "some fat" may increase "bioavailability  a little fat with the Riba can"t hurt ...however nothing to stress over....according to the company that makes it and most knowledgeable Hepa"s

Will

[Magnum]

In the past 4 treatment attempts, fat with Riba was never mentioned.

Magnum

[Magnum]

In the past 4 treatment attempts, fat with Riba was never mentioned.

Magnum

[hrsepwrguy]

Ribavirin has been around for a few more years and has been through all of the studies if not more than incivek, yet the label still doesn't call for fat intake before dose but the incivek does and how do you know that you are not absorbing to much riba which must be bad for you or they would say take 2000 mg's a day just to make sure you get enough. Riba is a major cause in hgb decline so maybe to much is not a good thing, but I guess maybe it is better to be safe than sorry right.

[shanro]

because it is better to be safe than sorry...

I haven't seen any research proving that it's bad to take riba with high fat, but there's research that it may be beneficial.  It seems that this is still being studied...  So why not just take the riba with high fat which won't do any harm..

as far as second guessing my doctor, the incivek protocol was studied... and in my opinion I'd rather be safe then sorry...

[hrsepwrguy]

Thank you for the clarification on the issue.