finally

[desperateforanswersone]

called my Dr after treatment being postponed over last four years waiten on next best treatment to come along and demanded I want to start treatment and yayy finally he's going to book me in for an ultrasound of my liver do a full blood count and kidney function test as had renal failure 17 years ago whilst on acycloveir antiviral meds for sepsis and if all checks out they r going to start me on triple treatment whatever that means. yes I'm scared to death of side affects but I'm more scared of hcv gt1. glad I found this site and found out more about hcv gt1 than I ever knew in the four years I've known I've had it

[Dee1956]

KoKo, I love that...just say no to interferon.  Good one :)

[keepingOnkeepingOn]

Just say no to Interferon. GT 1's only need S/O Solvadi Olysio. Treatment naive 12 weeks, all others 24 weeks. If treatment naive you may not need to get the QU 80 test. Your doc is reading the directions too hard. It says that about interferon on the directions but it is not needed. All the patients my doc has have cleared the virus on S/O. Be careful of height weight proportionate issues. Over 165 ilbs for a woman lessens your chances to clear unless you are 6 feet. Then I'd shoot for 24 weeks if not height weight proportionate.

[Dee1956]

Hi after looking at some of your posts I wanted to let you know you are not a good candidate for interferon.
If your doctor was knowledgeable he/she would know that it is contraindicated in anyone with anxiety to your extent.
He can write it up in a way to get you the Harvoni, if he can't there are other doctors.
Right now Gilead is helping people who are not approved by their insurance.
I was not a good candidate but there was nothing else at the time and I could not wait,  I had been waiting over 3 years when I treated.

http://www.mysupportpath.com/  (Gilead assistance)

http://www.panfoundation.org/       (Financial Assistance)

Take Care
Dee

[Dee1956]

Pooh is right, please don't use Interferon.  Please find another doctor.  If you have waited 4 years then you have been waiting for the all oral, not anything with interferon, Pegasys or Pegintron.
I am hoping your doctor means the new AbbieV and just can't count :)
I wish you the best
Dee

[pooh55811]

The current recommended treatment for treatment naive non-cirrhotic Genotype 1 patients is Harvoni for 12 weeks or the AbbVie drugs. Interferon is not needed. One can do all oral treatment now. If I was you, I would push for all oral treatment.

Also, be sure your doctor specializes in HCV treatment. Many GIs are not that good with HCV treatment. Especially if you have a history of renal problems you need someone who knows what they are doing if you develop complications. You also want someone who is up to date on the most current treatments and who will not stick you with an outdated Interferon based treatment.

Also, an Ultrasound won't tell you if you have Cirrhosis. Your doctor needs to do testing to determine how much liver fibrosis you have (liver biopsy or some of the other testing for liver fibrosis). If you have Cirrhosis, the treatment regimen is different, so you need to know if you have Cirrhosis or not.

"Initial Treatment Box. Summary of Recommendations for Patients Who are Initiating Therapy for HCV Infection by HCV Genotype"

"Three options with similar efficacy in general are recommended for treatment-naive patients with HCV genotype 1a infection (listed in alphabetic order; see text)."

"Daily fixed-dose combination of ledipasvir (90 mg)/sofosbuvir (400 mg) for 12 weeks* is recommended for treatment-naive patients with HCV genotype 1a infection.  (Harvoni)
*See text for further detail on length of treatment

Rating: Class I, Level A

Daily fixed-dose combination of paritaprevir (150 mg)/ritonavir (100 mg)/ombitasvir (25 mg) plus twice-daily dosed dasabuvir (250 mg) and weight-based RBV (1000 mg [75 kg]) for 12 weeks (no cirrhosis) or 24 weeks (cirrhosis) is recommended for treatment-naive patients with HCV genotype 1a infection.  (AbbVie drugs)

Rating: Class I, Level A

Daily sofosbuvir (400 mg) plus simeprevir (150 mg) with or without weight-based RBV (1000 mg [75 kg]) for 12 weeks (no cirrhosis) or 24 weeks (cirrhosis) is recommended for treatment-naive patients with HCV genotype 1a infection.

Rating: Class IIa, Level B"



Note that the following regimens are NOT recommended:

"The following regimens are NOT recommended for treatment-naive patients with HCV genotype 1.*

    Daily sofosbuvir (400 mg) and weight-based RBV (1000 mg [75 kg]) for 24 weeks.

    Rating: Class IIb, Level A

    PEG-IFN and RBV with or without sofosbuvir, simeprevir, telaprevir, or boceprevir for 12 weeks to 48 weeks.

    Rating: Class IIb, Level A

    Monotherapy with PEG-IFN, RBV, or a direct-acting antiviral

    Rating: Class III, Level A"



http://www.hcvguidelines.org/full-report/initial-treatment-box-summary-recommendations-patients-who-are-initiating-therapy-hcv

http://www.hcvguidelines.org/full-report-view

[flyinlynn]

Hey
I will say interferon was not a party but I did 6 months 3 different times.

You can do anything for just 12 weeks standing on your head

You can do this thing and be free on the other side!

[desperateforanswersone]

thanks so much I was starting to feel at a loss for what to do I think now my Dr is going to take me seriously I just hope the side affects aren't as bad as they say

[flyinlynn]

That would be Sovaldi 1 pill a day, plus peg interferon (shots) once a week, and Ribavirin probably 2 pills a day at different times of the day. for 12 weeks.

Here is the prescribing information sheet for Sovaldi

https://www.gilead.com/~/media/Files/pdfs/medicines/liver-disease/sovaldi/sovaldi_pi.pdf

Good luck