null responder

[almawe]

Just got the phone call, that after 4 weeks treatment with SOC and telaprivir, that l am a non responder. have to cease all medication at once.  Am in a  bit of shock.  dont know were to go from here.,  I am genotype 1a, CT and have mild to moderate fibrosis. it will be ery har sitting around doing 'nothing' for the hep c.  am already ready a healthy life style.  feeling very depressed.  l know there are others in my position.  

[somuchmore2]

Sorry about your recent news....

However, one thing to keep in mind  2 fibrosis is not so bad. Most livers will compensate with HCV for years or decades. All the stuff your're already doing is important to continue....good exercise, good intake of stuff, control other healh stuff.

Your input does bring me to pause on whether to wish for Tela or Boce.  With stage 4 cirrihois I am thinking one of these will likely be my final shot at the HCV prior to TP listing.

[willbb]

  Hi there...I also had less than stellar results in a trial....therefore discontinued tx. There are a number of us here.


However with aprrox.40 new drugs in the pipeline there will be something for us in the future....so as nygirl says...treat that thing like gold for now and   and as Magnum says.."try try again"

Positive thoughts your way....

Will

[nygirl7]

I['m sorry what a damn crappppppy thing to happen.  But I agree with Magnum once the tela and boce get out there into the mix you should try with a doctor not in a trial where you can see all the info and act accordingly. I mean what if your VL was down to 50 or something - they'd still kick you because of their rules but would you stop if it was that low? I sure wouldn't.

Or maybe you needed more riba or a different interferon there are a lot of things that could be tried that they wouldn't have done in a trial.  And I agree with Upbeat you should get that test and see what it says.

They are working on non-ifn/riba drugs and hopefully one will come out soon as a stage 2 you do have time just treat that liver like it's gold and you certainly have time to wait for them.

I'm so sorry my thoughts are with you.

[Upbeat]

Just curious.  Did you ever have a Ll28b test done?  

[Magnum]

"If at first you don't succeed, try try again", a great man once said. This will be my 5th attempt, and if that doesn't work, refer to the start of this paragraph. A fact that many should understand about this disease, is that many many more go to their graves with it  rather than from it.

Never give up, never give in....

Magnum

[almawe]

Another question...is the protocol on length of time to decide if treatment is not working ( ie 4 weeks in my case) the same for all those about to start treating with the new drugs...and wishing all the best of luck..exciting times for you.