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Avatar universal

Desperate for help

I'm hoping someone can give me some answers:
My symptoms started in 2008 and has been progressing slowly.
1. I have tingling and pins-and-needles throughout my body.
2. ALL my joints ache randomly
3. Just had physical done, all were normal EXCEPT my netrophil counts are LOW.
4. Both lupus and RA were negative
5. Headaches too
What do you think this is? Anyone with similar symptoms that had help from doctors? I'm desperate for guidance.
God bless.
3 Responses
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Avatar universal
Does anyone relate to this? I am awake now and can't sleep due to the leg muscle twitching, tingling body and joint pain.
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Avatar universal

Thank you for your response. I'm only 31 years old, but this is affecting me.  
1. Does MS also cause slight neutropenia?
2. I only ask because I've had this low neutrophil on my past 2 annual physicals, and my doc doesn't seem concerned.
I will follow up on the possible MS diagnosis, my doctor wrote me off when I suggested MS,  as he said the presentation/distribution is not suggestive of MS.
Thanks again, this is a true humanitarian service to devote your time so freely.

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Avatar universal
MEDICAL PROFESSIONAL
Hi there.  You need to be investigated for multiple sclerosis since you have multiple neurological symptoms suggestive of  MS. MS is a chronic demyelinating disorder where the disease phase is characterized by active phase and remissions. It has multiple symptoms and signs and is a diagnosis of exclusion. The symptoms of multiple sclerosis are loss of balance, muscle spasms, numbness in any area, problems with walking and coordination, tremors in one or more arms and legs. Bowel and bladder symptoms include frequency of micturition, urine leakage, eye symptoms like double vision uncontrollable rapid eye movements, facial pain, painful muscle spasms, tingling, burning in arms or legs, depression, dizziness, hearing loss, fatigue etc. The treatment is essentially limited to symptomatic therapy so the course of action would not change much whether MS has been diagnosed or not. Apart from clinical neurological examination, MRI shows MS as paler areas of demyelination, two different episodes of demyelination separated by one month in at least two different brain locations. Spinal tap is done and CSF electrophoresis reveals oligoclonal bands suggestive of immune activity, which is suggestive but not diagnostic of MS. Demyelinating neurons, transmit nerve signals slower than non-demyelinated ones and can be detected with EP tests. These are visual evoked potentials, brain stem auditory evoked response, and somatosensory evoked potential. Slower nerve responses in any one of these is not confirmatory of MS but can be used to complement diagnosis along with a neurological examination, medical history and an MRI in addition, a spinal tap. Neutropenia could be due to a viral infection, side effect of a drug, or exposure to certain poisons or if you are on chemotherapy for cancer. Neutropenia makes you susceptible to infections, most of them in lungs, mouth, throat, sinuses and skin. Painful mouth ulcers, gum infections, ear infections and periodontal disease. Therefore, it would be prudent to consult your neurologist with these concerns. Hope this helps. Take care.

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