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Can R-cinex and Combutol cause Edema?

My brother was given both the drugs R-Cinex 600 and Combutol 600 with Supradyn, Razo D and Mesicof syrup. His tests for tuberculosis were constantly negetive but he was still administered these drugs for 12 days. He developed Edema. Could these drugs be the cause for his Edema?
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