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Difference btw hydrocodone and oxycodone?

What is the exact difference between hydrocodone/Vicodin/ loratab and oxycodone/ Percocet? I know Percocet is supposed to be lil stronger but what is the real difference? Does one work better on other pains? What's the difference btw hydro and oxy? Thanks!!
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Avatar universal
Here is an article about the subject
http://ethehealthadvisor.com/oxycodone-vs-hydrocodone/

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Avatar universal
You know daddysgirl600 and savak, who cares if you're dependent on a medication prescribed by your doctor whether it's a narcotic or not, whether you take it and it makes you feel sleepy, or calm or even loopy. It doesn't necessarily mean you're addicted even medically speaking. Hear is the medical definition of addiction.

Habitual psychological and physiological dependence on a substance or practice beyond one's voluntary control.

I take solace in those last words in the definition. I am prescribed Norco 10mg/325. I have been taking hydrocodone for eight years regularly and much longer than that if I had an occasional severe pain situation. I didn't want to increase my refills from six months on average to every other month to monthly and increase my mg and dosage but my doctor and I felt it was the best option available to me and I am always allowed to take them as needed. I do have a withdrawal symptoms if I don't take one for a day or two, and the withdrawal strength can vary depending on if I took my full daily doses or needed less and if this was  for one day, or a week straight , I have never wanted to go and take a pain pill for NON PAIN withdrawal symptoms(unless I mistake them for candy, even for a second. But that's rare now that I don't  keep any pills in my pez dispensers lol:). Now, many of my family members are prescribed a wide assortment of medications, and if they miss one dosage on most of these and not just things that are obvious, like psyche-meds, but just maintanence type meds, like for cholesterol, blood pressure or blood thinners, their withdrawal symptoms are much more severe than my worst withdrawal session and it's definitely more mental addiction than what I deal with because if I can figure out what's wrong with that person and give them the dosage missed, they immediately have a reduction in symptoms. Even before that damn thing could hit their stomach they feel and act a major reduction in symptoms. Yep, mind over matter on that but they can't do it without having that pill head down their throat. So there you go, who gives a **** if people are addicted to something that will help them lead a better quality of life? As long as you aren't going rogue on your meds and trying to get a high, you are only trying to improve your quality of life, same thing doctors used to always be able to help us with without worrying about breaking a law, or more likely, not being able to get an HMO, or a medical insurance company, or maybe even a hospital bureaucracy to allow our doctors to do their job.
Sorry I went off about that, but I get a lot of guff from one person in my family for taking narcotic pain relievers and I don't think we should have to worry about 'addiction' and all the nastiness it entails when we aren't doing this to get by, be high or ignore life.
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Avatar universal
All of you with itching caused by these or any drugs (and/or foods for that matter) PLEASE pay attention to your body's reaction...a little topical itching is one thing. But... as a rule of thumb, if you are itching on the outside, what is it doing to you on the inside?? A true allergic reaction can be life threatening. Sorry--the nurse in me just had to say that. And...Best of luck with your pain management!
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7721494 tn?1431627964
All opioids cause a histamine release in mammals, which is dependent on dose, route of administration, and heterogeneity of the patient.

This is why most people itch when taking opioids. Opioid-related itch can be treated with an oral antihistamine, for instance, 25-50mg of benedryl.

In extremely rare occasions, opioids can cause a true anaphylactic reaction that requires a full emergency response including airway management and treatment with injectable antihistamine and/or epinephrine.

Many people who have an allergic response to strong opiates like morphine but do not actually express a true immunoglobulin-mediated allergy, will show an intolerance to the drug. In this case, anesthesiologists will often substitute hydromorphone without incident.
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Avatar universal
Funny, I was just discussing this with my doctor yeterday.

I think its been well explained here that oxycodone is MUCH stronger than hydrocodone.   But if you really want to know, the only difference from a pharmacological point of view, is that on the 14th carbon, with Hydro, there is an 'H' atom, and with oxy, there is a hydroxyl group ("OH".)

I have a degree in pharmacology and am fascinated by how such a tiny change can have such an enormous effect on the human body.

In my state, a doctor can phone in a script for hydrocone.  But oxy?  NO way. You have to physically bring in the piece of paper yourself.
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Avatar universal
I have been taken both hydrocodone and oxycodone for seven years the latter for 6 3/4 yrs the hydrocodone was just prescribed tome with slow release morphine pills. I have stop taking or I should miss taking my medication every once in a while and I get no mental withdraw problems but I do get extreme pain in my back ( I have 2 crushed disc in my back,and the only reason I don't have an operation is everyone I have talked to have been in worse shape than when they were before their operation,some needing several more of them with same results) but I have found the combination of the morphine pills and hydrocodone I take less pill and have less side effects like constipation . I like the oxycodone for keeping the pain away better but I would like to get one of these Meds without Tylenol because my liver enzymes have been going up had hepatitis c got rid of it and I don't want to get it again, the treatment almost killed me.
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