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363243 tn?1331033850

Sensitivity to Thyroid Medication

What do you do if you have a sensitivity to synthetic thyroid hormone, when a small dose is taken you also have to take a beta blocker to counteract the tachycardia, you're a poor T4 to T3 converter and you're endocrinologist doesn't want to prescribe a T3 medication because of "cardiac contraindications" so you continue feeling like crap?
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Avatar universal
Your story sounds like mine in a lot of ways.  I have a congenital heart defect, so I've had episodes of tachycardia all my life.  It never required meds, until I started levo.  Long story short, my PCP started me on way too high a dose of levo (88 mcg), and I had to back off and back off down to 25 mcg, and still my tachy was going wild.  I was having 20-30 episodes per day as opposed to 3-4 per year before levo.  Enter the beta blocker.  I've been on beta blockers ever since...I don't think a lot of taking one drug to counter the side effects of the other, but I have Hashi's as well, so not taking thyroid meds is not an option.

In your original post, you imply that you're a slow converter.  I really don't see that in the labs immediately above.  Your FT4 is at 24% of range, and FT3 is at 33%.  Both are lower than many of our members are comfortable at, but your ratio of FT3 to FT4 does not indicate a conversion problem.  It looks quite good, actually.  A conversion problem is usually indicated when FT3 is lower in its range than FT4 is in its.

More questions...I'm sorry...do you have your March labs to compare FT3 and FT4 after stopping meds.  The trend is often the most telling part.  You said you hadn't been taking your levo regularly before these labs...what exactly had you been taking?  What adrenal tests did they do, and how did they come out?

Your TSH did go down after stopping meds, but TSH is very volatile (it can even be affected by the time of day the blood was drawn), and I would not even consider 8.2 to 7.2 a significant difference.  However, in both cases, TSH is well above range, so apparently your pituitary "thinks" your levels are too low as well.

As the antibodies compromise thyroid function, they unfortunately don't do it on a nice, gentle downward slope.  There's often a lot of sputtering and fluctuating from hypo to hyper.  It's possible that in March your thyroid was producing a bit more than it had been previously, causing your trip to the ER.  However, at this point, your labs look like you are in need of meds.
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1139187 tn?1355706647
Coco,  which beta blocker are you on?  Propranol and enderol are good choices.  They come in low doses.  It's what marksman take to steady their hands when they are shooting rifles.   Some of the beta blockers be direful and do not take if your blood pressure less than 110/70.
Helpful - 0
1139187 tn?1355706647
Paus,  you should start your own thread.  May be easier, but you know you can get your thyroid by mail?   There are pharmacies that will ship to you.   I don't think I want to tell you to decrease your dose because am not a dr.   For me, the itching went away after three days.  It was mainly at night when I slept.   Did you get tested for hashimotos?
Helpful - 0
363243 tn?1331033850
Goolarra, the beta blocker does seem to help some. I found out that the left lobe of my thyroid is markedly atrophied and the radiologist didn't know if it had been surgically removed. I'm not sure how this affects my diagnosis of Hashimoto's because I haven't heard of this before.

Paus, how long have you been having these symptoms? If I were you I would ask my doctor to lower the dosage and slowly build it back up.
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1671473 tn?1450592437
Brucergoldberg, hi i think your  right, but my regular dose since 2008 is 150mcg of synthroid  but since synthroid are no longer available here in Phil. i take thyrax 150mcg, do i need to decrease my dose?
Helpful - 0
1671473 tn?1450592437
hi, I only have hypothyroidism, my dr. said just to continue my 150mcg (Thyrax) thats my regular maintenance. why im experiencing right now a tremor, shaking hands,feet, head, & cold feet, cold hands, & i feel weak sometimes,  am i having a hypothyroid symptoms or just a side effect,?
Helpful - 0
Avatar universal
What about the beta blocker?  Any luck with those?
Helpful - 0
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