I've been experiencing extreme fatigue, swelling, painful joints and muscles for many years now. I recently saw new P.A. for a routine exam and mentioned these ongoing complaints. She did some blood work and informed me I tested low positive for something that could indicate Lupus. She did more blood work, and just told me the Lupus test was negative, but my SED rate was elevated at 27. I've had these and other complaints for almost 20 years now. I've been diagnosed with Depression and I take meds for that. I'm just sooooo tired and sore, what do I do now?