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Hydrocodone/Acetaminophen Overdose at over 72 hours...

Okay so heres the breakdown:

Sunday night I bought a bunch of hydrocodone 7.5/Acetaminophen 650-- 30 of em. I went through most in the following days

5 pills/2600 mg  (Sunday)

7.5 pills 14 hours later 4875 mg   (Mon)

6 pills 23 hours later 3900 mg   (Tues) (with attempe\ted CWE which I dont believe worked correctly)

5 more pills 8 hours later 3250 mg  (Tuesday night at 7 pm, no CWE)




Its been approx 80 hours since my last dose and I was reading online that 72-96 hours is where liver failure occurs from acetaminophen overdose.... I havent had any serious symptoms yet-- I didnt have any vomitting/nausea within 24 hours of any doses, however had slight abdominal pain that almost felt like it was the more squishy material connected to my ribs themselves kinda right below of my sternum. The pain came and went and didnt worsen much but seems to become more persistent. My head is starting to ache a little bit now and I have pressure in my lower abdomen that feels like just gas...

I guess my question is; at this point in time am I in the clear or in the highest danger zone? If I went to the ER at this point would they even be able to do anything for me?

No lectures please, I know I'm a drug addict-- thanks.
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Avatar universal
It doesn't matter if he stops taking the sub for a day while he takes the hydro's. it takes 72 hours for the sub to get out of his system anyways, so he's just fooling himself. Thats why he's taking so many trying to get a buzz,
As long as he resumes before the sub is out of his system, he won't feel wd's much if at all.
If however he waits too long, he could cause precipitated withdrawals when he resumes the subs and has too much hydro in his system, in which case he deserves it anyways.
Poison control won't be much use to him at this point either. Any "antidote" for acetaminophen poisoning has to be given within hours, not days later.
The only thing he can do at this point is go see if he still has any liver function left. If he killed it, the toxins from his dead liver will gradually shut down his kidneys as well as they build up.   Dead livers don't hurt at this point. He'll feel his kidneys a bit before they shut down though.  Then the pancreas will fail, and the grenade goes up in the gut feeling occurs. He'll feel that a lot. He'll go to the hospital then, he won't be able to stop himself.  It's very painful, and he'll be getting sicker by the second.  

There is no point sugar coating what he is possibly doing to himself. He'll either smarten up and go get help, or he'll just go try get high some more until he does.  
Helpful - 0
Avatar universal
Your liver is located  just under your ribs more to  your right side. An acetaminophen overdose causing liver damage would cause pain in that area.
And note, that once liver damage occurs, there is no "antidote"
Any "antidote" for acetaminophen poisoning is typically given, and only effective within the first hour or so of ingestion.  days later is of no use. It's already done it's damage and is out of the body 4-5 hours after taking it.

If you caused liver failure, the pain goes away, and between 24-72 hours later the toxins it releases begin to act on your kidneys, and will shut them down also.

If you are still urinating at this point then that probably hasn't happened. But if your urine is very dark , brownish, and smelly, then you have done some damage, and should get to the hospital for assessment.

As for the headaches, that's just Tylenol withdrawal.

Taking subs after taking hydrocodone isn't a good Idea, but nothing you are doing is.
Why you are  prescribed subs in the first place is mind boggling, as it's a crappy pain killer, and you don't get a buzz from it either. All it does is prevent you from getting a buzz from other opiates. That's what it's supposed to do.

Since you don't want to quit abusing drugs apparently, You are going to continue playing Russian roulette with your liver. If it isn't dead already, it soon will be, as will you.
There is no "cure" or "antidote" for liver failure, and subsequent kidney failure. You will just get a few days extra life while on dialysis to say so long to everyone before you die.  It isn't likely that you will recieve a liver transplant, as there are others who aren't trying to kill themselves who would receive any that come available.

Good luck with whatever life you have left since you "aren't ready" to quit abusing drugs. Personally I think you were ready long ago, so does your liver, if it's still alive.  


Helpful - 0
1700643 tn?1464846682
Honestly TO ME it sounds like ur having w/d pains.Thats A LOT of buffer though+that can give u pain+discomfort and both that amount of buffer+w/d cause headaches
Helpful - 0
Avatar universal
HI the E/R wil just bill you some blood work will telll you where you stand everybody is different I use to eat them by the hand full and never had any problems or go lucky or mabe God was watching over me look at it this way you would just blow the money on dope anyway it worth saving your life over
this is nothing to mess with you have taken a lot over several days in a row
your liver can only metabolize so much and your over the limit for that time frame GO TO THE E/R.........Gnarly
Helpful - 0
1235186 tn?1656987798
ok. give them a call.
thats great you were able to give up the needle.
i hope i didnt sound judgemental. i am sorry i said "you wanted to get high"
that was wrong of me.
please give us an update, we do care.
yes in time you will stop.
Helpful - 0
Avatar universal
and there are free emergency health care clinics here in TX, but thats a long way away from Canada....
Helpful - 0
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