I find that cortisol (a stress hormone) gets low over time when people have prolonged stressful problems. For example, chronic food allergies (like grain allergy) can stress the body and result in "beaten down" adrenals over time and give low cortisols. The thyroid antibody means that your immune system is attacking your thyoid. Since traditional medicine has us convinced that our parts function separately rather than as a single operating system, its hard to fathom that a problem in one part of the body can manifest as a symptom in another. However, GI problems can --> a myriad of other symptoms throughout the body. Food ingredients like gluten can make our own immune system begin to attack our own body. Medicine has simply been naming the disease based on the location of the attack (Celiac disease is the GI attack; Graves and Hashimoto's are thyroid attacks; Rheumatoid arthritis is a joint attack; Psoriasis is a skin attack; MS a nervous system attack on myelin; etc. When the adrenals are low there is a "stressful" reason. Stress is broader than just worry. It can be infectious; from an injury, nutrient deficiency, toxicity, etc., as well as emotional. Look for other autoimmune disorders in your family like the above and see if the people in your gene pool are gluten intolerant. Inflammation in the intestines can make you vulnerable to things like appendicitis, diverticulitis and a number of other " itis' " which always means inflammation.
Most definately
But I don't think the appendix had anything to do with that though.