Aa
Aa
A
A
A
Close
Avatar universal

Celexa vs Zoloft

I think I am going to switch from Zoloft to Celexa.  I am going to my doctor this week to ask about it.  I KNOW that we all are different & every medicine will affect us on a different level, but is there a difference between the two?  I hope I don't have the same side effects I had on Zoloft.  
Best Answer
480448 tn?1426948538
All SSRIs are appropriate to be used as an anxiety treatment, despite being classed as an anti depressant.  Instead of YOU deciding which med you want, you're better off explaining to your doc what has been going on, and see what he recommends.

While two meds might both be SSRIs, they all work a little differently in their mechanism of action.  The end result is the same (an increased amount of serotonin in the brain)..but how you get there is different with each med, hence why there are so many varying experiences.

Cymbalta tends to be a bit activating, so that may not be the best choice, ask your doctor about it.  There's no way to predict how you will do on something else, but let's hope well.  I STRONGLY urge you to have a back up plan in place to help deal with any side effects,  should they occur.  A short acting benzo would be appropriate.  I know you're fearful after your experience with Xanax but it's worth a try.  Ativan tends to be a little less intense, so you could try that.  Again, mention it to your doctor.  Whatever you do...don't make any changes...stay on your current dose of the Zoloft until you get in to see him.


Again, remain open mided.  Do NOT go into the doctor's office with a mind full of what you will or won't take.  Let the doctor make some recommendations, then have a discussion from there.  With the new world of google, we are all so quick to want to play doctor...lol.

Good luck....update us on the new plan.
50 Responses
Sort by: Helpful Oldest Newest
Avatar universal
I had zero side effects from Lexapro and it worked really well for me for eight years.  It's the only SSRI that didn't cause me any bad side effects; Celexa wasn't too bad either, but it didn't work well for me.  I'm the same...barely get out of bed, anxious all the time.  I've been on the Zoloft for over a month now and don't see any improvement, but my doctor wants me to give it another two weeks...oh...and now I have hand tremors.  :)
Helpful - 0
Avatar universal
That makes me feel better.  Thank you.  When he said that Paxil was sedating but then mentioned the side effects (possible drug interactions, not so good on the liver & excessive weight gain) I chose the Lex.  Did you have any start up side effects?  I plan to start it tomorrow night.  =)  How have you been?
Helpful - 0
Avatar universal
I think you made a good choice.  Lexapro is literally the only SSRI I've taken that has not caused severe side effects.  I have a very difficult time with drugs and this one was a godsend for me.  (I've tried Celexa, Zoloft, Paxil, & Effexor.)  I took the generic for a month and didn't notice any difference in it's effectiveness versus Lexapro.  
Helpful - 0
Avatar universal
I was tempted to go with Paxil despite everything my doctor said.  I hope I made the right choice with Lex.
Helpful - 0
Avatar universal
Lexapro is 10 mg and Valium is 2mg (once a day).  Does this sound like a good start?  
Helpful - 0
Avatar universal
I am not sure but when I get them later I will let you know.  Let's hope this does the trick!  I hope it doesn't cause shakes like Zoloft did.  
Helpful - 0
Have an Answer?

You are reading content posted in the Anxiety Community

Top Anxiety Answerers
Avatar universal
Arlington, VA
370181 tn?1595629445
Arlington, WA
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
Find out what can trigger a panic attack – and what to do if you have one.
A guide to 10 common phobias.
Take control of tension today.
These simple pick-me-ups squash stress.
Don’t let the winter chill send your smile into deep hibernation. Try these 10 mood-boosting tips to get your happy back
Want to wake up rested and refreshed?