Bipolar Disorder Community
Antihistamine and Psychiatric medication (lithium,lamictal,treliptal)
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Bipolar Disorder is also known as "Manic Depressive Disorder". This forum is for questions and support for people with, or for loved ones of people with Bipolar Disorder. The forum covers topics ranging from Aggressive Behavior, Affect on friends and Family, Alcohol and Drug Abuse, Appetite Changes, Chronic Pain, Denial, Depression, Difficulty Concentrating, Euphoria, Guilt, Manic Depression, Medications, Mood Swings, Poor Judgment, and Sleep Disorders

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Antihistamine and Psychiatric medication (lithium,lamictal,treliptal)

Hi everybody

i would like to know if any one uses antihistamine meds such as(Claritine) for eye allergy or any other form of allergy.

my doc prescribed it and i have been searching for meds interaction on (www.rxlist.com) and nothing was listed there.

however it is written that it might cause (( agitation, amnesia, anxiety, confusion, decreased libido, depression, impaired concentration, insomnia, irritability, paroniria.)) as side effects but in a very low percentage .


it also says in CLINICAL PHARMACOLOGY section
((Whole body autoradiographic studies in rats and monkeys, radiolabeled tissue distribution studies in mice and rats, and in vivoradioligand studies in mice have shown that neither loratadine nor its metabolites readily cross the blood-brain barrier. Radioligand binding studies with guinea pig pulmonary and brain H1-receptors indicate that there was preferential binding to peripheral versus central nervous system))

i understand both sentence except how come the meds does not cross the blood brain barrier yet it causes the above side effects???????????

am gonna consult my pdoc ,,,but i really appreciate any info or experience on antihistamine meds and psychiatric meds in general

thx for reading

2 Comments Post a Comment
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I take a variety of psych meds.  I also take Benadryl and Zyrtec for my really bad allergies.  I have never had any problems.  This is slightly off subject but I recently had a cold and took Nyquil.  I became psychotic and delusional until it wore off.  Just a warning. No one ever told me.
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Almost all psychiatrists can easily access a database as regards medication interactions and inform you which ones you can't take. I know one of my medications interacts with asprin and Motrin but not Tylenol. However, there can occasionally be interactions that are adverse reactions but uncommon. One thing that's essential is to inform your psychiatrist about every medication you are taking as prescribed by another doctor or over the counter as they might not think to ask about it and might not know in general. Likewise any general practicioner should be informed about what psychiatric medications you take. I've had a couple of antiobiotics that made me psychotic and ones they prescribe now instead.
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