Luvox and seizures

My 8 yr. old son has epilepsy and Tourettes.  He was recently given Luvox 25 mg b.i.d.  He took this for two weeks for OCD, but I noticed that he had a lot of bruises appear - legs, arms, stomach.  The psychiatrist said to stop the Luvox as it may be related to the bruising.  He was on no other med, no AED as his neuro had stopped his AED in August to see if seizures returned since he hadn't had any since about April.  The first day he had no Luvox he had a complex partial seizure.  The following day he had 10 seizures and ended up in the ER to be given IV Dilantin.  My question is this, could Luvox have lowered his seizure threshold and could it have caused the easy bruising?  If so, would that mean he would be unable to take other SSRI's for his OCD?  I should mention that his bloodwork taken two days after stopping the Luvox showed his creatinine, bilirubin and alkaline phos were out of range on the low end.  It also showed his WBC and neut % to be out of range on the high end.  No mention was made of this by the ER doc, but I wonder if this is Luvox-related or maybe he just had some kind of minor infection.

Thank You

[Roger Gould, M.D.]

This is a complex case because of the seizure issues and your neurologist is the best one to guide you here. When you read the fine print on Luvox and other ssri's, you see that this kind of reaction is possible, but very difficult to prove. It doesn't meant that it will happen again, so cautious re-trial of a ssri could be done under medical supervision.