Does Prilosec Shut Off ALL acid production?

I am 55 yo healthy male.I have a hiatal hernia which was caused by my body bloating up from an allergic reaction to pennicillian in 1986. I have suffered from heartburn ever since, and tried to control the burning fire in the esophagus with all the usual OTC remedies and diet,raising the head of bed etc.etc.One year ago I started taking OTC Prilosec, 1 pill a day, and It works perfect for me and I lead a normal life.and no side effects.When I stop the prilosec, the heartburn comes back in a couple of weeks. my question is, does prilosec shut off ALL the stomache acid, or does it leave a little for food digestion? Is that why you should only use it for two weeks every 4 months? Can I take prilosec for ever? I dont want to risk FundoplicationHiatal hernia repair surgery. Thanks .

[Ratnakar Kini, MD]

Hi,
Prilosec is relatively safe medication. It can be taken for a longer term if there is definite indication.
It decreases the acid output.
The effect depends on the dose used.
20 mg prilosec inhibits upto 80% and 40 mg prilosec upto 95% of acid secretion.
But it can cause 100% inhibition of acid secretion.
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The information provided is for patients’ education only and is not a medical advice. Always consult your personal physician for complete evaluation of your health problem.

- Ratnakar Kini M.D.