Chronic hepatitis B

[asiafem722]

65 y.o. female, found positive for Hepatitis B in 1998. Her first LFT shown
AST (41/41), ALT 36/45. ordered by my primary care MD:

HB E Antibody POSITIVE, HB E Antigen negative, HB SAg (surface antigen) POSITIVE, HB Surface Antibody Negative
Hep A negative, Hep C negative

In Oct 11, 2000 under care of GI/hepatologist, LFT gave:
AST 399/36, ALT 583/39.
In Nov 06, 2000
HBV DNA Quantitative gave  HBV DNA 24200 copies/mL
HBV DNA (pg/mL)  0.085 pg/mL
Lamuvidine was mentioned but not started due to the fact that HBV DNA viral load less than 50000-100000 copies/mL

In Jan 12, 2001, LFT gave:
AST 26/36, ALT 21/39

In Dec 12, 2002 LFT gave:
AST 50/31, ALT 81/30.
US liver, all other test (EGD, Colonoscopy, MRI) normal.

In Jan 10, 2003
AST 32/30, ALT 34/30

In Jan 25, 2006
HBV DNA viral load 719 copies/mL
In Feb 09 2006
HBV DNA 3770 copies/mL
alpha-fetoprotein 6.7 IU/mL (limit 0-15 IU/mL)
In 2007: US liver, other tests: NORMAL

Recently  In June  07 2010 LFT gave:
AST 31/49
ALT 28/55
Alpha-fetoprotein 2.3 ng (limit 0-8.3) by Roche Eclia method
In June 22 2010, labs gave:
HBV Real-time PCR Quant :  HBV 7650 IU/mL
HBV DNA 44500 copies/mL (1 IU= 5.82 copies)
G.I specialist wants to put on VIREAD 300 mg once daily.
Ultra sound liver on June 29 2010 is normal
Hepatitis C and A negative


Since HBV DNA viral load is 44,500 copies which is still under the limitation to treat (< 50,000-100,000 copies/mL).
Should she hold and have another vival load count in December before making decision?

[stef2011]

mild diarrea like when you take antibiotics, if you take probiotics you avoid it, most of us have had a mild diarrea once that resolved in 2-3 days

How long should I take it before I go for the test.
i'd test after 4-8-12 weeks if you can afford the tests otherwise directly after 6 months, hbsg kinetics are very slow, also check hbsab one in the ntz group with hbsag 800iu/ml made antibody at 200miu/ml in one month but a the third month antibody disappered, he was on the low dose 1g daily and this low dose was not effective on nobody until now

[Jojo997]

Thank you
I'm waiting for my doctor if he can find me some
then I see the way forward.
How long should I take it before I go for the test.
Is there any side effects?

[stef2011]

using nizonide500 the most important test is hbsag quantity in iu/ml, hbvdna and alt/ast are less important

[stef2011]

the producer is lupin from india, you can order from canadian pharmacies but maybe you will find it in your country or southafrica too since it was approved as an anti-diarrea active on rotavirus and parassites/bacteria which are common in your country and south africa

they did not submit approval in europe since rotavirus or parassites are rare here so it is not marketed in europe, in italy you can have it only inside hospitals

[Jojo997]

Thanks so much for the relieve given me.
Actually the lab where I took my test is
a subsidiary lab from South Africa, they
are more advanced in such things. The
lab here acts as collection point of such
cases and sent to the main lab in South
Africa and you get the results in a week
time. They call it Hepatitis B Profiling
and they use Roche Taqman Assay.
They did LFT, HBV & DNA Viral Loads
and the HB Profiling on me.

I have just called my doctor to check if
he can get me the Nizonide500. Can I have
some from Italy? I have a friend there who
can help.

Your response is greatly anticipated.
Thank you.  

[satimis]

Forever Bee Pollen, the said to be Healthcare Supplement:  

On Internet I found many articles describing its functions.  Most of them are advertisement.  But I can't find a medical report with scientific proof on its function in curing chronic Hep B.  Could any folk on this forum pointing me the URL in this respect?  TIA

B.R.
satimis