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3242225 tn?1348336521

Anyone want to see a great article?

http://www.natap.org/2012/HCV/072712_01.htm
Here is a summary of what Gilead is doing in it's atempt to get 7977 to market but in addition, it's attempt to go for the holy grail of creating a once a day pill for all genotypes.  They say in this article that they are very close. I believe them. I'm been involved in one of their clinical trials and this company literally brings tears to my eyes in how ethical and just plain decent they are in the way that they are treating patients.  so, here's a good one to give everyone the hope that a side effect free once a day pill is coming that can cure all genotypes.  It's coming..
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Avatar universal
I was probably the initial person that cried foul when Gilead decided not to partner with BMS. However, I now see the bigger picture. Gilead are in fact combining 7977 with 5885 (their own NS5a) into one pill and the next trial will have it. I definitely see the reason for them wanting only one pill. If one pill can get to market, it's going to make eradicating this virus, that much easier. People can remember to take ONE pill, as opposed to several. 7977 is in phase 3 and 5885 has been around for a good while now. They actually know a lot about it and it's comparable to BMS' NS5a.
I don't understand anyone saying it's put the cure back ten years! Gilead will be filing for FDA approval next year for 7977+riba for geno's 2 and 3 and look to hopefully follow that up in 2014 for geno 1's with 7977+5885.
What does one mean that they'll stop research? When you have the cure, you have the cure! Gilead have never stopped research with HIV. In fact they're the leading pharma in that department and I would say that the world should be very happy about that. Personally, I'm feeling very good about what they have to offer.
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Avatar universal
I think what people don't get is that if it wasn't for the profit we wouldn't have five companies with HCV drugs in Phase III trials right now.  And they ferociously compete against each other to get to market first so they can make those profits.

I think it's crazy when I hear people bash big pharma especially when the bashers are in other countries (I'm on an international hcv email list) but meanwhile most of the great drugs come out of the US and the US medical complex.  People want great drugs and then complain they are expensive and that they're being held up by pharmaceutical companies.  The drugs wouldn't be there if there wasn't this system and the capitalist profit motive.

I say more power to Gilead and this system.  They and their ilk are gonna have cures for us sooner than later.

Even the regulatory had picked up to get drugs through to market faster.  It's a little ridiculous how they have to do trials now but still the drugs are coming.  Witness all the people on this board trying them and many getting good results.
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3097131 tn?1357084881
I SECOND THE MOTION!!!
~Country~
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446474 tn?1446347682
UKgirl, I agree with your assessment.

I guess some people think that having drugs the manage diseases like HIV and other potentially fatal diseases is 'bad' in their perfect 'everything should be free' world scenarios. Not sure what country they live in because the last time I went to the store I actually had to pay for what I wanted.

Let's see... Gilead paid 10.8 billion dollars to acquire Pharmasset. So they should give GS-7977 away for free? Does anyone work for a company that uses this business model? I doubt it. Your company wouldn't be in business for too long. Gilead has the only drug that achieves RVR 100% of the time, has a high barrier to resistance, has minimal side effects even when combined with ribavirin and has higher cure rates then the current triple therapy with interferon. They should just give it away? How about a little reality check.

Everyone is free to treat or not treat their hepatitis C, so it is not like Gilead or any other pharma company is forcing anyone to treat with or buy their drug. People are free to make their own choices as far as medical care is concerned. If you don't want to treat fine. But why criticise others for their choices?

Of course there there are people on this forum that have promoted their conspiracy theory's for years and said the same thing about telaprevir and boceprevir not that long along. It was the end of the world. Another scheme by pharma, the FDA and doctors to make more money and rip patients off. Nothing original here.

Please go to the Hepatitis Social forum where you can pontificate your theories. This forum is supposed to be for informing people about the facts of diagnosis and treatment. Not personal theories that have no factual basis.

It is depressing to realize that even others who have or have had hepatitis C have no compassion for those of us that have run out of options and are suffering the full consequences of hepatitis C, liver failure and/or liver cancer.

Hector

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85962 tn?1329981090
Profits over life, Sad but a cold hard fact!
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Avatar universal
First time I ever heard the word decent and pharm company mentioned in the same sentence. The Pharm companies make a lot of people cry, but not because they adore the company :-)

Sorry but all pharm's treat their "guinea pigs" great! You are helping to make them billions in the future.
Don't get me wrong I was a lab rat myself. I'm very grateful to Vertex for "curing" me of HCV.

Anyway it is great the pharms continue to find better treatments. I don't see any single dose hcv drugs hitting the market for many years to come.

best of luck
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