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1689583 tn?1387752394

Incivek or Victrelis

I will be tx 1st time in 2012 , how does hep doc know which one to use . Is it based on liver damage nd vl or is it a personal choice.
Best Answer
446474 tn?1446347682
From Sermo’s community of over 120,000 physicians, our analysts conduct market research and compile detailed reports that closely examine physician opinion of market trends and developments.

"Which New Hepatitis C Drug do MDs Prefer?:
Incivek (telaprevir) vs. Victrelis (boceprevir)

http://hepatitiscnewdrugs.blogspot.com/2011/10/hey-doc-victrelis-boceprevir-or-incivek.html

Background:

Physicians ( 65 Gastroenterologist & 36 Infectious Disease & 6 others) were provided three recent news articles about Incivek (telaprevir) and Victrelis (boceprevir) and asked to compare these two new hepatitis C drugs:

*    Gauge the awareness level and use of these new treatments
*    Evaluate the "real-life" efficacy of each drug with current patients
*    Predict which product will become the standard of care

Executive Summary

*    Overall, more than 90% of surveyed physicians confirmed that they are aware of the approval and availability of both Incivek and Victrelis.

*    21% of physicians are only prescribing Incivek compared to 8% who are only writing Victrelis.

*    Efficacy was listed as the top strength for both drugs. MDs identified the following individual strengths for each drug:

*       Incivek: Often Shorter Duration of Treatment Plan, Simple Regimen/Fewer Pills. Best for prior Null Responders. More potential for 24 weeks of treatment. Less severe anemia.

*       Victrelis: Less Frequent Rash, Tolerability
    
34% of physicians tapped Incivek to become Standard of Care (SOC)

Percentage of MDs Prescribing Each Drug

    Over half of physicians are already prescribing both new drugs
    Of those physicians who are only prescribing one drug, 21% are prescribing Incivek; while only 8% are writing Victrelis

Physicians Identified Top Strengths of Incivek

    MD respondents selected efficacy as top strength of Incivek
    Strengths listed for Incivek over Victrelis included: Often Shorter Duration of Tx and Simple Regimen/Fewer Pills

Physicians Identified Top Strengths of Victrelis

    MD respondents selected efficacy as top strength of Victrelis
    Strengths listed for Victrelis over Incivek included: Less Frequent Rash and Tolerability

Patients Response to Both Drugs

    Physicians asked for more data from Victrelis on co-infected patients as well as more data from both drugs on efficacy in HIV+ patients

Physicians Weigh in on Standard of Care

    34% of physicians tapped Incivek to become Standard of Care
    55% of physicians were unsure if either of these products would be the next Standard of Care"

Hector
11 Responses
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1689583 tn?1387752394
Thank you as much as I do not like the fat intake and possible problem with rash , the success rate is higher and tx time is lower so I was originally leaning towards Vic but the shorter tx time and less pills is looking pretty good at this stage . At least the option is available , for yourself I can understantand why you chose Vic .So glad to her you are UND you will make it .
Helpful - 0
Avatar universal
Express your concerns and med history carefully w/hep doc. I'm glad I'm on Vic b/c I'm prone to excema and had rash issues due to riba. My present anemia is holding around 9-9.5. The bad news is that I'll be opn Vic longer than 12 weeks-the pills  get tougher to swallow as the day progresses. The great news is I'm UND for wks 8 and 12 vl's.
Helpful - 0
1689583 tn?1387752394
Thank you Hector, and yes , I will take your advice it has been a while since I last posted .Thanks.
Helpful - 0
1747881 tn?1546175878
All prior threads you started are automatically stored in your watch list on your home page, really easy to find.
Helpful - 0
163305 tn?1333668571
I'd like to suggest making a file to keep your information in.
You can do it on your computer or write things down and keep them filed.

I know its often hard to remember.
I cut and paste items all the time.
Then I can refer to my files to refresh my memory.
Helpful - 0
Avatar universal
"Normally it is based on prior tx history.  Incivek is the one for relapsers, non-responders or second or more tx's."

Where did that come from? Never heard that before. Many prior relapsers here that are SVR now.
Helpful - 0
1689583 tn?1387752394
Thanks for reminding me I reread it .
Helpful - 0
Avatar universal
Helpful - 0
1815939 tn?1377991799
Some doctors may feel one drug is better than the other for various reasons. Some doctors use both drugs and they may decide to use one over the other depending on other health issues a person has and/or the side effects. Or the patient may prefer one over the other. Some doctors prefer one over the other and use only one of them. I know my doctor uses only Incivek.  
Helpful - 0
408795 tn?1324935675
Normally it is based on prior tx history.  Incivek is the one for relapsers, non-responders or second or more tx's.  That said, you may be able to choose your weapon depending on the doctor and your circumstances.  good luck
Helpful - 0
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