Multiple Sclerosis Community
Botox approved for Urinary Incontinence
About This Community:

Our Patient-to-Patient MS Forum is where you can communicate with other people who share your interest in Multiple Sclerosis. This forum is not monitored by medical professionals.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Botox approved for Urinary Incontinence

HI All,

I received this update on one of the medical sites I use and thought there might be some interest. Botox has been used off-label for urinary incontinence but it is FDA approved which may help those whose insurance won't pay for off-label use of drugs. The article is shown below:

FDA NEWS RELEASE
For Immediate Release: August 25, 2011
Media Inquiries: Jeffrey Ventura, 301-796-2807, jeffrey.***@****
Consumer Inquiries: 888-INFO-FDA

FDA approves Botox to treat specific form of urinary incontinence

The U.S. Food and Drug Administration today approved Botox (onabotulinumtoxinA) injection to treat urinary incontinence in people with neurologic conditions such as spinal cord injury and multiple sclerosis who have overactivity of the bladder.

Uninhibited urinary bladder contractions in people with some neurological conditions can lead to an inability to store urine. Current management of this condition includes medications to relax the bladder and use of a catheter to regularly empty the bladder.

The treatment consists of Botox being injected into the bladder resulting in relaxation of the bladder, an increase in its storage capacity and a decrease in urinary incontinence.

"Urinary incontinence associated with neurologic conditions can be difficult to manage,” said George Benson, deputy director, Division of Reproductive and Urologic Products. “Botox offers another treatment option for these patients."

Injection of the bladder with Botox is performed using cystoscopy, a procedure that allows a doctor to visualize the interior of the bladder. Cystoscopy may require general anesthesia. The duration of the effect of Botox on urinary incontinence in patients with bladder overactivity associated with a neurologic condition is up to 10 months.

The effectiveness of Botox to treat this type of incontinence was demonstrated in two clinical studies involving 691 patients. The patients had urinary incontinence resulting from spinal cord injury or multiple sclerosis. Both studies showed statistically significant decreases in the weekly frequency of incontinence episodes in the Botox group compared with placebo.

In addition to its use to improve the appearance of facial frown lines, Botox also is FDA-approved to treat chronic migraine headaches, certain kinds of muscle stiffness and contraction, severe underarm sweating, abnormal twitch of the eyelid and a condition in which the eyes are not properly aligned.

The most common adverse reactions observed following injection of Botox into the bladder were urinary tract infection and urinary retention. Those who develop urinary retention after Botox treatment may require self-catheterization to empty the bladder.

Botox is marketed in the United States by Allergan Inc., of Irvine, Calif.

For more information:

What is Botox?1

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.
Related Discussions
2 Comments Post a Comment
Blank
199882_tn?1310188142
This is great news Ren... Thank you so much for the information!!!!

I'll be praying,
Carol
Blank
572651_tn?1333939396
Funny- I was typing up the same announcement when you were posting this as well.  It is great news.
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Multiple Sclerosis Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Neurology Answerers
572651_tn?1333939396
Blank
Lulu54
Dayton, OH
Avatar_f_tn
Blank
SarahL2491
Alagash, ME
987762_tn?1331031553
Blank
supermum_ms
Australia
Avatar_f_tn
Blank
essdipity
338416_tn?1413581329
Blank
jensequitur
Fort Worth, TX
667078_tn?1316004535
Blank
HVAC
Durham, NC