I was diagnosed in April 2010, and started taking Copaxone in November. I haven't had any of the tightness in my chest or rapid heart beats or anything, but at the injection sites I have been having massive swelling. I understand that there will be a reaction, but it is lasting for days, feels on fire through my pants, and is about the size of both of my fists put together and the patches are rock hard! Why?? Is anyone having any kind of reaction like that? I have rotated the hot/cold packs and neither way is making it better! If anyone has any advice I would appreciate it so much.