Aa
Long time no see. I normalized one antibody that was high since '97.
Long time no see. think I posted a couple years ago, other than that its been a few years and I must say this new format they kept is not user friendly compared to the old one. I cam back wondering if any new people have lowered their antibodies as this was a hot topic once thought to be impossible. I asked several folks in that past who "assumed" their antibodies were better after some other treatment to please fill in the blanks with details (lab tests). No one would do this. No proof then. Have people shown this to happen here in the last few years? I actually normalized one of my two thyroid antibodies (proof on two tests in one years time). So only one antibody normalized, could say I was half successful. I still need my pig thyroid though- no level change (bummer). I do feel a little better, but I've done so much healthwise with holistic approaches, its hard to say if it was from better diet, diet healing a gut, or candida control, or all of the above.
Great to hear from you Moose. We have missed your participation on the forum.
What is your thyroid med and dosage now? What do your Free T4, Free T3, Vitamin D, B12 and ferritin tests show?
What is your thyroid med and dosage now? What do your Free T4, Free T3, Vitamin D, B12 and ferritin tests show?
1 Comments
Why do I have the option to comment or answer for further dialog? Whats the difference?I dont remember the old format having that (?)
Not at home, no test data on me. I 've still been increasing my dose about every 9 months or so- same pattern as usual. My usual good lab has TSH below 2, ft4 at 30% and ft3 at 70% roughly. I am a little hypo right now and need my yearly increase.
I switched to NP about three years ago after trusting it on the market a few years. Was on Erfa before. Stopped monitoring b12 and D-25 a year ago. Those had no noticable effect on me, and levels were good, dried different brands too.
I am in not way saying I'm healed or anything LOL, !!
Just surprised that two latest antibody tests showed one normalized. So I would expect to feel even better than I do.
Time will tell, as my diet is a working experiment. I had gut issues my whole life, now on a super healthy diet my gut feels great. They say a healthy gut = a healthy immune system and response, time will tell. Not home now, dont remember if it was tpo or tgab that corrected, but I do have the proof on paper. Hopefully it wont bounce back. If I went back to eating my old ways, and retested elevated, than I know it was diet related / influence. But I'm not about to abandon my anti-inflammatory modified paleo diet just yet.
Another important fact is I treated with antibiotics for lyme disease two years ago. Lyme disease can have an effect on immune system. So killing that off can have other positive effects. To many variables in my case.
Whatever the case, if I want to track my thyroid antibodies, I'll have to pay for it. Endo and insurance wont repeat this testing, as they both think its forever, thus no need to track it. Well, guess its not forever in all cases.
LM
I switched to NP about three years ago after trusting it on the market a few years. Was on Erfa before. Stopped monitoring b12 and D-25 a year ago. Those had no noticable effect on me, and levels were good, dried different brands too.
I am in not way saying I'm healed or anything LOL, !!
Just surprised that two latest antibody tests showed one normalized. So I would expect to feel even better than I do.
Time will tell, as my diet is a working experiment. I had gut issues my whole life, now on a super healthy diet my gut feels great. They say a healthy gut = a healthy immune system and response, time will tell. Not home now, dont remember if it was tpo or tgab that corrected, but I do have the proof on paper. Hopefully it wont bounce back. If I went back to eating my old ways, and retested elevated, than I know it was diet related / influence. But I'm not about to abandon my anti-inflammatory modified paleo diet just yet.
Another important fact is I treated with antibiotics for lyme disease two years ago. Lyme disease can have an effect on immune system. So killing that off can have other positive effects. To many variables in my case.
Whatever the case, if I want to track my thyroid antibodies, I'll have to pay for it. Endo and insurance wont repeat this testing, as they both think its forever, thus no need to track it. Well, guess its not forever in all cases.
LM
COMMUNITY LEADER
Hey there, LazyMoose... long time, no see. We have missed you. A lot of our old regulars left are gone; perhaps they'll straggle back in...
The comment and answer boxes are somewhat redundant, but they can be used interchangeably... If someone asks a question and we want to answer it, we're supposed to use an answer box (white box), then when we want to comment, we're supposed to use the blue comment boxes, but those allow side conversations to get started - what I consider "hijacking" a thread. You'll get the hang of it... lol
It's interesting about your antibody count. Mine went way down (only slightly elevated) and my doctors quit monitoring them because they said my Hashimoto's was "in remission" because my thyroid was burned out.
I've recently switched from an endo to a Nurse Practitioner, who takes a more holistic approach, to manage my thyroid because my TSH is still in the basement and I'm tired of doctors insisting I'm hyper, just because my TSH is non-existent, when my FT levels aren't even above mid range. The NP doesn't give a rip about TSH, but she wondered why they stopped monitoring antibodies and she looked at me like I had 2 heads when I told her they'd said my thyroid was dead. She ordered TPOab and it's back up again...
What diet are you on, how long have you been on it and how did you come to start it? I'm a firm believer that a healthy gut is important, but I can't seem to get my doctors on board with me. I went through a bout of H. Pylori the first of the year. I see my new NP on Monday and I'm hoping she will be more helpful than previous doctors have been, as far as diet is concerned.
The comment and answer boxes are somewhat redundant, but they can be used interchangeably... If someone asks a question and we want to answer it, we're supposed to use an answer box (white box), then when we want to comment, we're supposed to use the blue comment boxes, but those allow side conversations to get started - what I consider "hijacking" a thread. You'll get the hang of it... lol
It's interesting about your antibody count. Mine went way down (only slightly elevated) and my doctors quit monitoring them because they said my Hashimoto's was "in remission" because my thyroid was burned out.
I've recently switched from an endo to a Nurse Practitioner, who takes a more holistic approach, to manage my thyroid because my TSH is still in the basement and I'm tired of doctors insisting I'm hyper, just because my TSH is non-existent, when my FT levels aren't even above mid range. The NP doesn't give a rip about TSH, but she wondered why they stopped monitoring antibodies and she looked at me like I had 2 heads when I told her they'd said my thyroid was dead. She ordered TPOab and it's back up again...
What diet are you on, how long have you been on it and how did you come to start it? I'm a firm believer that a healthy gut is important, but I can't seem to get my doctors on board with me. I went through a bout of H. Pylori the first of the year. I see my new NP on Monday and I'm hoping she will be more helpful than previous doctors have been, as far as diet is concerned.
Avoid the blue box- got it. What got me into healthy eating was researching for lyme disease treatment and how to boost your own immune system since lyme can attack your immune system, nervous system, and endocrine system. I did use conventional antibiotics to, but many herbal and natural supplements are incorporated in its treatment - at least in cases where your whole body is messed up. Obviously regular Drs dont do this. I saw three "Functional MD's" who practice a combination of natural and Rx medicine - they do it all and have incredible knowledge of the human body systems. I avoided Holistic chiropractors trying to be "Drs", - some are good I hear, but you need to weed out the quackery. They cant provide Rx or have access to medical lab testing either.
One thing they preach is that healthy low inflammation eating can help your body overcome illness by supporting your own immune system. How much you give up in healthy eating, depends how far you desire to go. I did it gradually and then full bore this year. I also have documented inflammation and immune tests that show progress as I progressed with a healthy diet. While I was trying to improve these (they did) , I decided to test thyroid antibodies and was surprised that my TPO was also normalized, the last two times. TGAB was still elevated.
Lyme bacteria, among other things can mess up your gut big time. I had holistic lab tests that showed leaky gut and conventional blood tests that showed systemic candida with antibodies formed against it. Had Reflux in the past to. I tried individual diets for each of these with some success then went all out (below) last winter.
I eat paleo, zero real milk products, no added sugar (real or fake), and was zero grains. I added non-gmo grains recently but avoid glutan. Was never a hard drinker, made it through summer with only two beers on the 4th of July. Sometimes this is called an autoimmune diet. This would be impossible for highly the social-dinning people.
I never read / studied the th1 or th2 diets- the Drs I saw didn't have much to say about it, so I currently remain neutral in that subject area. Different approaches work for different people based on their existing health.
So I dont know if keeping this diet will improve my thyroid any more, but since its improving other areas, I will stay on it longer. And retest, ...but I'll have to pay for it, insurance wont repeat things they feel is not needed.
With lyme, you pay out of pocket or dont get much better, sad but true. What makes some lyme patients worse than others is all in how their specific immune system responds to the foreign bacteria. Plus Lyme is in the spirochete bacteria family, very similar to Syphilis, hard to eradicate. Remember, Syph killed many people 100-150 years ago.
LM
One thing they preach is that healthy low inflammation eating can help your body overcome illness by supporting your own immune system. How much you give up in healthy eating, depends how far you desire to go. I did it gradually and then full bore this year. I also have documented inflammation and immune tests that show progress as I progressed with a healthy diet. While I was trying to improve these (they did) , I decided to test thyroid antibodies and was surprised that my TPO was also normalized, the last two times. TGAB was still elevated.
Lyme bacteria, among other things can mess up your gut big time. I had holistic lab tests that showed leaky gut and conventional blood tests that showed systemic candida with antibodies formed against it. Had Reflux in the past to. I tried individual diets for each of these with some success then went all out (below) last winter.
I eat paleo, zero real milk products, no added sugar (real or fake), and was zero grains. I added non-gmo grains recently but avoid glutan. Was never a hard drinker, made it through summer with only two beers on the 4th of July. Sometimes this is called an autoimmune diet. This would be impossible for highly the social-dinning people.
I never read / studied the th1 or th2 diets- the Drs I saw didn't have much to say about it, so I currently remain neutral in that subject area. Different approaches work for different people based on their existing health.
So I dont know if keeping this diet will improve my thyroid any more, but since its improving other areas, I will stay on it longer. And retest, ...but I'll have to pay for it, insurance wont repeat things they feel is not needed.
With lyme, you pay out of pocket or dont get much better, sad but true. What makes some lyme patients worse than others is all in how their specific immune system responds to the foreign bacteria. Plus Lyme is in the spirochete bacteria family, very similar to Syphilis, hard to eradicate. Remember, Syph killed many people 100-150 years ago.
LM
lazy moose,
I am interested in how you feel otherwise with the immune diet.
mainly, do you find yourself not catching every dang cold that comes by etc? Did you loose weight? Do you have more energy? Has it significantly increased your cost for food going I assume organic? Did the rest of your family also go on this diet, or are you having to cook and prepare separate foods especially for you?
My family went on the "whole30" diet a couple years ago. It was very successful and we all lost weight and felt better. But we "fell off the wagon" and have not gotten back on. I have been trying to get my wife (who does the grocery shopping) to just buy compliant food and eventually that is all we will have in the house to eat. But I have not yet been successful.
My wife is also on NDT only and has had several health issues over the last year. Not sure her thyroid dose is optimized yet. Dr's with her other health issues have yo-yo'd her around with thyroid meds. Her latest is rapid heart rate (NOT from being hyperthyroid) and knee pain.
Leading up to her hemolytic anemia issue, wife was adding in T4 in order to get her FT4 levels up while maintaining the Armour dose. Then with rapid heart rate (we thought associated with the anemia) they cut out the T4. Then after her anemia situation was cleared, she remained high heart rate, so they started to cut her Armour dose, since her TSH was supressed. As expected and as we told the Dr's, she felt like crap even after two reductions, and the heart rate did NOTHING and remained high. So we FINALLY got the Dr within the last two months to go back to her full dose of Armour (180 mgs), with zero added T4. She feels better, but still has heart rate issue. We have not yet sought for addition of T4 again to see if getting her FT4 levels even into the bottom of the range.
It appears the knee pain may be arthritis (She got cortisone shot into the knee last week) X-rays, PT and MRI showed nothing unusual.
My wife is overweight so by going to whole30 or similar diet with low inflamation, and lose weight would seem to be a win-win situation for her. But so far I am losing that "argument". I guess dealing with knee pain and eating what she wants is fine with her - LOL
I am interested in how you feel otherwise with the immune diet.
mainly, do you find yourself not catching every dang cold that comes by etc? Did you loose weight? Do you have more energy? Has it significantly increased your cost for food going I assume organic? Did the rest of your family also go on this diet, or are you having to cook and prepare separate foods especially for you?
My family went on the "whole30" diet a couple years ago. It was very successful and we all lost weight and felt better. But we "fell off the wagon" and have not gotten back on. I have been trying to get my wife (who does the grocery shopping) to just buy compliant food and eventually that is all we will have in the house to eat. But I have not yet been successful.
My wife is also on NDT only and has had several health issues over the last year. Not sure her thyroid dose is optimized yet. Dr's with her other health issues have yo-yo'd her around with thyroid meds. Her latest is rapid heart rate (NOT from being hyperthyroid) and knee pain.
Leading up to her hemolytic anemia issue, wife was adding in T4 in order to get her FT4 levels up while maintaining the Armour dose. Then with rapid heart rate (we thought associated with the anemia) they cut out the T4. Then after her anemia situation was cleared, she remained high heart rate, so they started to cut her Armour dose, since her TSH was supressed. As expected and as we told the Dr's, she felt like crap even after two reductions, and the heart rate did NOTHING and remained high. So we FINALLY got the Dr within the last two months to go back to her full dose of Armour (180 mgs), with zero added T4. She feels better, but still has heart rate issue. We have not yet sought for addition of T4 again to see if getting her FT4 levels even into the bottom of the range.
It appears the knee pain may be arthritis (She got cortisone shot into the knee last week) X-rays, PT and MRI showed nothing unusual.
My wife is overweight so by going to whole30 or similar diet with low inflamation, and lose weight would seem to be a win-win situation for her. But so far I am losing that "argument". I guess dealing with knee pain and eating what she wants is fine with her - LOL
3 Comments
Has your wife been tested for her FT4 and FT3 lately? Also, has she been tested for cortisol, Vitamin D and ferritin? If so, please post all those, with ranges, of course..
Last time she was tested for these for the vitamins was some time ago. But she has not changed her supplements since:
B-12 date 11/2016 tested > 1000 (239-931)
D3 date 3/2014 91 (30-100)
Ferritin date 11/2016 187 (6.2-137.0)
Iron 11/2016 74 (37-170)
FT4 6/14/2017 0.9 (0.7-2.19) = 8.5% of range
TSH = Suppressed barely detected.
FT3 6/14/17 3.66 (2.77-5.27)=35.6%
upped These thyroid tests was when she was at 50 mcg T4 and 150 mg Armour. Since changed to remove all T4 and back up to 180 mg Armour and wife is feeling better.
Cannot remember cortisol test. If it was done it was a long time ago and was in "normal rage" whatever that means.
Over time her sex hormones were tested three different times. Progesterone and estrogen normal at about 25% of the range for each. Testosterone however was one test zero percent of range, the other two tests well BELOW range.
Cannot get wife to follow up on the low testosterone. Even though she has several of the common low T symptoms FOR WOMEN.
If recall "my story" struggled for YEARS, as in probably nearly a decade, or more, to get my wife to follow up with Thyroid and fight for proper dosing.
Now she seems to be following the same pattern with "fighting" me on trying to deal with the potential of low Testosterone.
B-12 date 11/2016 tested > 1000 (239-931)
D3 date 3/2014 91 (30-100)
Ferritin date 11/2016 187 (6.2-137.0)
Iron 11/2016 74 (37-170)
FT4 6/14/2017 0.9 (0.7-2.19) = 8.5% of range
TSH = Suppressed barely detected.
FT3 6/14/17 3.66 (2.77-5.27)=35.6%
upped These thyroid tests was when she was at 50 mcg T4 and 150 mg Armour. Since changed to remove all T4 and back up to 180 mg Armour and wife is feeling better.
Cannot remember cortisol test. If it was done it was a long time ago and was in "normal rage" whatever that means.
Over time her sex hormones were tested three different times. Progesterone and estrogen normal at about 25% of the range for each. Testosterone however was one test zero percent of range, the other two tests well BELOW range.
Cannot get wife to follow up on the low testosterone. Even though she has several of the common low T symptoms FOR WOMEN.
If recall "my story" struggled for YEARS, as in probably nearly a decade, or more, to get my wife to follow up with Thyroid and fight for proper dosing.
Now she seems to be following the same pattern with "fighting" me on trying to deal with the potential of low Testosterone.
Unless she is supplementing with a lot of iron, the high ferritin indicates she should follow up and get a full iron test panel of serum iron, TIBC, %saturation and ferritin again.
Regarding testosterone, there is a lot of unnecessary concern about supplementing. You can depend on the info in this link. It might also help your wife get over any concern she has.
http://www.hormonerestoration.com/Testosterone.html
Regarding testosterone, there is a lot of unnecessary concern about supplementing. You can depend on the info in this link. It might also help your wife get over any concern she has.
http://www.hormonerestoration.com/Testosterone.html
Im my experience, ERFA and NP acella (both NDT) absorb better than the few other brands, thus FT4 is a little higher than the others. T3 does not bind to protiens, thus does not seem to matter amongst NDT brands.
I also did the whole30 version of Paleo for first three months, now just a little less strict (some non-gmo grains now). Yes it costs a little more, but clean eating is more popular today and its now more affordable. This is easier for less-social introverts such as myself LOL (live alone). I do less social eating today, and if its outdoor summer social eating, I pack my own food. I feel physically better to some extent, not in a huge way, but it is noticable. Long term will tell I guess. This would be tough for high social and or family people.
Paleo in general has a more positive effect than organic + no-Paleo. So many "organic" eaters also eat non-paleo, then whats the point? I'm not 100% organic, not in meats or veggies. Since Paleo is whole foods, one does not consume the slury of gravies laced with glutan and chemicals, and animal milk (typical midwest "hot-dish" meal is a big no no). My gut feels the best ever in my life.
This is somwhat of and over due experiment on health. In my early 50's but always tried to have an active outdoor lifestyle, so I had only a little weight to lose anyway, by by 5lb.
I also did the whole30 version of Paleo for first three months, now just a little less strict (some non-gmo grains now). Yes it costs a little more, but clean eating is more popular today and its now more affordable. This is easier for less-social introverts such as myself LOL (live alone). I do less social eating today, and if its outdoor summer social eating, I pack my own food. I feel physically better to some extent, not in a huge way, but it is noticable. Long term will tell I guess. This would be tough for high social and or family people.
Paleo in general has a more positive effect than organic + no-Paleo. So many "organic" eaters also eat non-paleo, then whats the point? I'm not 100% organic, not in meats or veggies. Since Paleo is whole foods, one does not consume the slury of gravies laced with glutan and chemicals, and animal milk (typical midwest "hot-dish" meal is a big no no). My gut feels the best ever in my life.
This is somwhat of and over due experiment on health. In my early 50's but always tried to have an active outdoor lifestyle, so I had only a little weight to lose anyway, by by 5lb.
Sounds interesting.
I also am in my early 50's. And I would like to lose about 8 to 10 lbs which by most popular height/weight BMI type charts would put me about at the top of normal, or very bottom of the overweight category. My wife on the other hand, in order to get to that same place on the chart has more weight to lose. And I think if I want to remain alive, is all I will say about my wife's weight! LOL!
On the whole 30, I didn't find any food sensitivities. My wife and daughter did with gluten. Makes them feel jittery, anxious similar to if they had too much caffeine.
To go back on the "whole30" modified, I will probably not give up dairy completely. I have switched to coconut milk almost exclusively. About the only dairy I have is cheese and occasionally yogurt. (and frozen yogurt from time to time). So keeping cheese in my diet seems pretty safe.
I think the main weight loss are from two factors. #1, staying away from added sugar and stuff that has added sugar in it. and #2, staying away from gluten. Not so much of the gluten itself, but rather all the foods that gluten is in, such as breads and gluten pasta's etc.
Another challenge for me being a big meat eater is staying away from processed meats. I LOVE bacon, Ham, Salami, summer sausage, jerky etc.
Also potato chips are my nemesis. But I have found lays "simple" and also some chips that are cooked in avocado oil. They are not strictly on the diet, but are about as good a "cheat" as I can find without completely blowing it. Like anything else. Just having enough will power to not overdo the "cheat" is the key.
Do you do any other added probiotics? Do you eat fermented veggies, Kombatchu etc?
I also am in my early 50's. And I would like to lose about 8 to 10 lbs which by most popular height/weight BMI type charts would put me about at the top of normal, or very bottom of the overweight category. My wife on the other hand, in order to get to that same place on the chart has more weight to lose. And I think if I want to remain alive, is all I will say about my wife's weight! LOL!
On the whole 30, I didn't find any food sensitivities. My wife and daughter did with gluten. Makes them feel jittery, anxious similar to if they had too much caffeine.
To go back on the "whole30" modified, I will probably not give up dairy completely. I have switched to coconut milk almost exclusively. About the only dairy I have is cheese and occasionally yogurt. (and frozen yogurt from time to time). So keeping cheese in my diet seems pretty safe.
I think the main weight loss are from two factors. #1, staying away from added sugar and stuff that has added sugar in it. and #2, staying away from gluten. Not so much of the gluten itself, but rather all the foods that gluten is in, such as breads and gluten pasta's etc.
Another challenge for me being a big meat eater is staying away from processed meats. I LOVE bacon, Ham, Salami, summer sausage, jerky etc.
Also potato chips are my nemesis. But I have found lays "simple" and also some chips that are cooked in avocado oil. They are not strictly on the diet, but are about as good a "cheat" as I can find without completely blowing it. Like anything else. Just having enough will power to not overdo the "cheat" is the key.
Do you do any other added probiotics? Do you eat fermented veggies, Kombatchu etc?
I added non-gmo corn chips as my only chip "cheat", only has 4 ingreadiants. Still do bacon on occation, but with no antibiotics, nitates or sugars. And bison or natural suages for processed meats (whole30). My "diet" is not a weight loss plan, but could be if I needed to be.
Not on any probiotics, natural, supplimented or fermented for 9 months. I did consume them years ago when first trying to correct leaky gut with gut candida. The correct natural food in its natural state, seemed to eliminate this past need.
Yogurt is a commercial joke- look at all the sugar in it! same with Kerfir. Candida eats sugar and carbs.
I dont feel good after any milk products, so I eliminated all of it. Almond milk is my new friend. Some of them have to many chemicals too so not all brands are equal.
Not on any probiotics, natural, supplimented or fermented for 9 months. I did consume them years ago when first trying to correct leaky gut with gut candida. The correct natural food in its natural state, seemed to eliminate this past need.
Yogurt is a commercial joke- look at all the sugar in it! same with Kerfir. Candida eats sugar and carbs.
I dont feel good after any milk products, so I eliminated all of it. Almond milk is my new friend. Some of them have to many chemicals too so not all brands are equal.
1 Comments
oops....spell check was off
I found something very interesting on lowering thyroglobulin antibodies (TgAb)!
"The results of this study show a selective decrease in TgAb but not TPOAb levels in patients with Hashimoto's thyroiditis after 12 weeks of anatabine supplementation. Anatabine is an alkaloid found in plants of the Solanaceae family, including tobacco, tomatoes, potatoes, peppers, and eggplants (8).
Although the mechanism of action of dietary anatabine on thyroid autoimmunity remains to be elucidated, it may produce immunomodulatory effects through activation of α4β2 or α7 cholinergic receptors similar to nicotine and other structurally related agonists (9,–11).
In a mouse model of thyroiditis, anatabine decreases thyroidal IL-1β and IL-18 levels (7), and in other experimental disease models it suppresses the inflammatory transcription factors signal transducer and activator of transcription 3 and nuclear factor-κB (12,–14)."*
Solanaceae is also known as nightshades. My TgAb is usually in normal range as is my mother's. I believe my TgAb was a bit elevated a few years ago when I was first tested though. My mother's TgAb is usually normal..not sure if she has ever had elevated TgAb actually. I'd have to check all the labs.
But reading this study is interesting since my mother loves tomatoes. I bought 28 tomatoes at a local market and she ate them all in 2 weeks! I'm not a fan of eating tomatoes like that but I do like tomato sauce. We both like potatoes as well.
My mother had her testing done recently (she was in remission for Hashimoto's thyroiditis after she stopped taking acid blocker nexium and started betaine HCL with pepsin supplements and digestive enzyme supplements) but due to a lot of emotional stress had retriggered her hashi's (TPO rose again) but her TgAb is normal.
*Anatabine Supplementation Decreases Thyroglobulin Antibodies in Patients With Chronic Lymphocytic Autoimmune (Hashimoto's) Thyroiditis: A Randomized Controlled Clinical Trial
J Clin Endocrinol Metab. 2014 Jan; 99(1): E137–E142.
Published online 2013 Oct 31. doi: 10.1210/jc.2013-2951
"The results of this study show a selective decrease in TgAb but not TPOAb levels in patients with Hashimoto's thyroiditis after 12 weeks of anatabine supplementation. Anatabine is an alkaloid found in plants of the Solanaceae family, including tobacco, tomatoes, potatoes, peppers, and eggplants (8).
Although the mechanism of action of dietary anatabine on thyroid autoimmunity remains to be elucidated, it may produce immunomodulatory effects through activation of α4β2 or α7 cholinergic receptors similar to nicotine and other structurally related agonists (9,–11).
In a mouse model of thyroiditis, anatabine decreases thyroidal IL-1β and IL-18 levels (7), and in other experimental disease models it suppresses the inflammatory transcription factors signal transducer and activator of transcription 3 and nuclear factor-κB (12,–14)."*
Solanaceae is also known as nightshades. My TgAb is usually in normal range as is my mother's. I believe my TgAb was a bit elevated a few years ago when I was first tested though. My mother's TgAb is usually normal..not sure if she has ever had elevated TgAb actually. I'd have to check all the labs.
But reading this study is interesting since my mother loves tomatoes. I bought 28 tomatoes at a local market and she ate them all in 2 weeks! I'm not a fan of eating tomatoes like that but I do like tomato sauce. We both like potatoes as well.
My mother had her testing done recently (she was in remission for Hashimoto's thyroiditis after she stopped taking acid blocker nexium and started betaine HCL with pepsin supplements and digestive enzyme supplements) but due to a lot of emotional stress had retriggered her hashi's (TPO rose again) but her TgAb is normal.
*Anatabine Supplementation Decreases Thyroglobulin Antibodies in Patients With Chronic Lymphocytic Autoimmune (Hashimoto's) Thyroiditis: A Randomized Controlled Clinical Trial
J Clin Endocrinol Metab. 2014 Jan; 99(1): E137–E142.
Published online 2013 Oct 31. doi: 10.1210/jc.2013-2951
I LOVE bacon. I just bought 2kg (4.4 pounds) of bacon actually. I've read Susannah Mushatt Jones (died age 116) ate 4 rashes of bacon with eggs daily and and the oldest living cats (died age 38 and 34) ate bacon and eggs daily as well.
Red Star- interesting about the alkaloid in night shades decreasing TgAb (the antibody I still have).. I say interesting because there are also sources that say nightshades should be eliminated in a "anti-inflammatory autoimmune diet". I might read up on that more, since my TgAb was still elevated. Confusing.
That said, I still eat nightshades like sweet peppers but replaced white potatoes with sweet potatoes. Guess that's where Paleo and Autoimmune diets differ.
My main quest was to see if there was anything I could through diet to help boost my immune system to rid whatever lyme or candida I have left....the natural way. The fact that it normalized my TPO was a coincidental surprise.
That said, I still eat nightshades like sweet peppers but replaced white potatoes with sweet potatoes. Guess that's where Paleo and Autoimmune diets differ.
My main quest was to see if there was anything I could through diet to help boost my immune system to rid whatever lyme or candida I have left....the natural way. The fact that it normalized my TPO was a coincidental surprise.
Red Star- interesting about the alkaloid in night shades decreasing TgAb (the antibody I still have).. I say interesting because there are also sources that say nightshades should be eliminated in a "anti-inflammatory autoimmune diet". I might read up on that more, since my TgAb was still elevated. Confusing.
That said, I still eat nightshades like sweet peppers but replaced white potatoes with sweet potatoes. Guess that's where Paleo and Autoimmune diets differ.
My main quest was to see if there was anything I could through diet to help boost my immune system to rid whatever lyme or candida I have left....the natural way. The fact that it normalized my TPO was a coincidental surprise.
That said, I still eat nightshades like sweet peppers but replaced white potatoes with sweet potatoes. Guess that's where Paleo and Autoimmune diets differ.
My main quest was to see if there was anything I could through diet to help boost my immune system to rid whatever lyme or candida I have left....the natural way. The fact that it normalized my TPO was a coincidental surprise.
I found this in regards to nightshades and inflammation...
Excerpt from the article What are Nightshades and Do They Cause Inflammation?...
"Because nightshades are only a problem for a small number of people, it’s overkill to suggest that everyone should avoid them.
People with arthritis are sometimes advised to avoid all nightshade plants because they are said to cause inflammation. But this advice really only applies to people who have a sensitivity to solanine. For these folks, eating nightshade plants causes an inflammatory reaction—including joint pain.
Because most people are not sensitive to solanine, however, I think it’s misleading to characterize nightshade plants as “inflammatory,” and it’s certainly overkill to suggest that everyone with arthritis should avoid them—especially because they have so much going for them nutritionally.
Nightshade plants are high in antioxidants, which actually help reduce inflammation. And chili peppers also contain capsaicin, a strongly anti-inflammatory compound. So, if you’re an arthritis sufferer, I’d think these would be foods you’d want to eat more of—unless, of course, you are among the minority that is sensitive to them."
**
I checked lab ranges and my mother's TgAb levels are always <10 (lab range is normal <60). When I first had Hashimoto's thyroiditis my TgAb was 150 but went back to <10 for 5 years until my most recent lab result (up to 120).
I'm not surprised at the increase in TgAb since I have severely depleted stomach acid due to chronic stress (causing a lot of deficiency states including iron deficiency anaemia) and stomach acid is crucial to good digestion/absorption and immune health. I need to start taking my mother's Betaine HCL with pepsin supplements.
My mother had severe systematic candida until she started betaine HCL with pepsin supplements and increased her stomach acid. Candida does not like an acidic environment. Probiotics are also acidic as well.
Excerpt from the article What are Nightshades and Do They Cause Inflammation?...
"Because nightshades are only a problem for a small number of people, it’s overkill to suggest that everyone should avoid them.
People with arthritis are sometimes advised to avoid all nightshade plants because they are said to cause inflammation. But this advice really only applies to people who have a sensitivity to solanine. For these folks, eating nightshade plants causes an inflammatory reaction—including joint pain.
Because most people are not sensitive to solanine, however, I think it’s misleading to characterize nightshade plants as “inflammatory,” and it’s certainly overkill to suggest that everyone with arthritis should avoid them—especially because they have so much going for them nutritionally.
Nightshade plants are high in antioxidants, which actually help reduce inflammation. And chili peppers also contain capsaicin, a strongly anti-inflammatory compound. So, if you’re an arthritis sufferer, I’d think these would be foods you’d want to eat more of—unless, of course, you are among the minority that is sensitive to them."
**
I checked lab ranges and my mother's TgAb levels are always <10 (lab range is normal <60). When I first had Hashimoto's thyroiditis my TgAb was 150 but went back to <10 for 5 years until my most recent lab result (up to 120).
I'm not surprised at the increase in TgAb since I have severely depleted stomach acid due to chronic stress (causing a lot of deficiency states including iron deficiency anaemia) and stomach acid is crucial to good digestion/absorption and immune health. I need to start taking my mother's Betaine HCL with pepsin supplements.
My mother had severe systematic candida until she started betaine HCL with pepsin supplements and increased her stomach acid. Candida does not like an acidic environment. Probiotics are also acidic as well.
Conventional medicine (anyone for that matter) really needs to get to he bottom of autoimmune illnesses. We are seeing the tip of the iceberg from the natural or functional medicine side- but its full of guesses. Its part genetics and seems to be influenced by diet. We know its not diet alone- cause a great part modern/western society would be ill from modern convenience/ junk food.
I tried a anti-oxalic acid diet (Dr suggest) for three months, which excludes nightshades, nuts ect. It did nothing so I checked that off the list.
I'll try my HCL again (even though I digest great) due to my candida past.
I tried a anti-oxalic acid diet (Dr suggest) for three months, which excludes nightshades, nuts ect. It did nothing so I checked that off the list.
I'll try my HCL again (even though I digest great) due to my candida past.
My first autoimmune disease showed up when I was baby. Not sure of the trigger but there are many possible triggers mentioned such as environmental toxins. I don't suffer from acid reflux regardless of stomach acid levels. I have to put that down to chewing my food excessively (B12 malabsorption damaged my gag reflex).
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Very interesting thread... sorry I had to bow out for a bit. I never did have elevated TgAb, though I did have elevated TPOab, which did go down after I started on thyroid hormones. I was told that was because my thyroid was "dead" and there was nothing left for the antibodies to attack, so they went into remission. They stopped testing antibodies for several years and as I noted above, my new NP just tested them and they're elevated again, so apparently, there's "something" left to attack...
I've also always had small nodules, never any dominant nodules though. That's changed now and I have one dominant nodule that's 1.1 X 1.0 X 0.8 cm. The ultrasound report stated that could be a thyroid or parathyroid nodule. Not sure how they could not tell the difference... I'll be sent to an ENT for follow up on that.
I've tried diet changes a couple of times, but it's been pretty difficult for a couple of reasons, mostly because it wasn't "doctor ordered", so family cooperation was slight to non-existent. It has been now doctor ordered, so it's going a bit easier. I've been asked to give up wheat, dairy, soy (which I ever eat anyway), sugar, processed foods (which I also don't eat much of), etc. I've only been trying it for a week, so haven't made a lot of progress and the sugar part of it is really difficult... :-(
I'm supposed to do an extensive stool sample, to check for a variety of parasites, since I did have H. Pylori at the beginning of the year, but that's all they tested for. I'll get that done this week.
Acid reflux has been one of my most prevalent symptoms for years - off and on. I've done the HCL with pepsin, which pretty well took care of the acid reflux. When I get it back, now, I take peppermint oil, dill pickle juice, etc to help restore acid.
My cortisol levels are also messed up, so that seems to be having an over-all effect, as well. In spite of having bi-lateral adrenal adenomas, the NP is the only one who has checked cortisol levels or thought it important to pay attention to them.
I'm finding it somewhat odd that after all these years, these things (dominant nodule, high TPOab, etc) would show up again after my thyroid was supposed to have been "dead".
I've also always had small nodules, never any dominant nodules though. That's changed now and I have one dominant nodule that's 1.1 X 1.0 X 0.8 cm. The ultrasound report stated that could be a thyroid or parathyroid nodule. Not sure how they could not tell the difference... I'll be sent to an ENT for follow up on that.
I've tried diet changes a couple of times, but it's been pretty difficult for a couple of reasons, mostly because it wasn't "doctor ordered", so family cooperation was slight to non-existent. It has been now doctor ordered, so it's going a bit easier. I've been asked to give up wheat, dairy, soy (which I ever eat anyway), sugar, processed foods (which I also don't eat much of), etc. I've only been trying it for a week, so haven't made a lot of progress and the sugar part of it is really difficult... :-(
I'm supposed to do an extensive stool sample, to check for a variety of parasites, since I did have H. Pylori at the beginning of the year, but that's all they tested for. I'll get that done this week.
Acid reflux has been one of my most prevalent symptoms for years - off and on. I've done the HCL with pepsin, which pretty well took care of the acid reflux. When I get it back, now, I take peppermint oil, dill pickle juice, etc to help restore acid.
My cortisol levels are also messed up, so that seems to be having an over-all effect, as well. In spite of having bi-lateral adrenal adenomas, the NP is the only one who has checked cortisol levels or thought it important to pay attention to them.
I'm finding it somewhat odd that after all these years, these things (dominant nodule, high TPOab, etc) would show up again after my thyroid was supposed to have been "dead".
Hey Barb, when my mother went into remission for Hashi's her thyroid nodules also reduced in size and some nodules disappeared. It looks like you were in remission (mistaken for a "dead" thyroid gland) and Hashi's has been retriggered for whatever reason (I found various reasons below) and affecting the size of your thyroid nodule.
You mention adrenal tumours and cortisol. Have you been tested for Cushing's Syndrome?
Except from the article from Restartmed: How Hashimoto's symptoms change over time + "flare" up symptoms...
"List of Hashimoto's flare up sources:
Extreme physiological or emotional stress (death of a loved one, divorce, problems at home/school/work, etc.)
Physical trauma such as car accident or even repetitive physical trauma from extreme exercising/sports
Chronic nutrient deficiencies
Viral infections (CMV, EBV, etc.)
Other hormone imbalances that may alter immune system function
Exposure to endocrine disrupting chemicals
Exposure to heavy metals (the removal of dental amalgams has been shown to reduce thyroid antibodies in some patients)
Increased intestinal permeability due to overgrowth syndromes or intestinal dysbiosis"
You mention adrenal tumours and cortisol. Have you been tested for Cushing's Syndrome?
Except from the article from Restartmed: How Hashimoto's symptoms change over time + "flare" up symptoms...
"List of Hashimoto's flare up sources:
Extreme physiological or emotional stress (death of a loved one, divorce, problems at home/school/work, etc.)
Physical trauma such as car accident or even repetitive physical trauma from extreme exercising/sports
Chronic nutrient deficiencies
Viral infections (CMV, EBV, etc.)
Other hormone imbalances that may alter immune system function
Exposure to endocrine disrupting chemicals
Exposure to heavy metals (the removal of dental amalgams has been shown to reduce thyroid antibodies in some patients)
Increased intestinal permeability due to overgrowth syndromes or intestinal dysbiosis"
COMMUNITY LEADER
Hey Red_Star... I'm not sure I was ever really in "remission", because my antibody count never did go completely back to normal; it just went down to less than 100 and the doctors quit testing it. Most of them have never really acknowledged that I really have Hashimoto's anyway. One of the actually listed "unspecified hypothyroidism" on my record - nowhere did he indicate that I have Hashimoto's.
I also don't believe that my nodules ever really went away. I think the one ultrasound that indicated such was an error. The doctor (my old endo) that ordered that ultrasound went out of practice less than a month after it was done, otherwise I think a follow up would have been ordered to verify its correctness.
I have never been tested for Cushings, because I don't have enough of the symptoms, though I do/did have a few of them, such as the excess hair (I had the facial hair lasered off, so doctors don't even know I had that...), of course, the weight issue, fatigue and high blood pressure. I do not have osteoporosis, as most with Cushings have. I do have some darkening and thinning of the skin in some places, but not the pad of fat between my shoulder blades or stretch marks. I have easy bruising, but not the anxiety, depression, hair loss, headache, round face, insomnia, etc.
I've had cortisol (abnormal) and epinephrine tests, but never the low-dose dexamethasone suppression test.
I think it's important that I take spironolactone as a diuretic, which affects the hormone adrenal aldosterone. It's not uncommon for aldosterone levels to be elevated when one has adrenal adenomas, but for some reason, neither my endo nor my pcp ever thought to remove me from the spironolactone and test aldosterone levels.
As for the Hashimoto's flare, right now, I'm putting my money on the high cortisol, nutrient deficiencies and out of balance gut bacteria... After having been wheat free for over a week, we went to an Italian restaurant for lunch today and I ate pasta and bread that I haven't been eating...Before I was even finished eating, I was burping and belching something awful and this evening, I feel like a bloated whale that's been washed ashore!!!
We'll see what comes of further testing, which was sent off yesterday.
I also don't believe that my nodules ever really went away. I think the one ultrasound that indicated such was an error. The doctor (my old endo) that ordered that ultrasound went out of practice less than a month after it was done, otherwise I think a follow up would have been ordered to verify its correctness.
I have never been tested for Cushings, because I don't have enough of the symptoms, though I do/did have a few of them, such as the excess hair (I had the facial hair lasered off, so doctors don't even know I had that...), of course, the weight issue, fatigue and high blood pressure. I do not have osteoporosis, as most with Cushings have. I do have some darkening and thinning of the skin in some places, but not the pad of fat between my shoulder blades or stretch marks. I have easy bruising, but not the anxiety, depression, hair loss, headache, round face, insomnia, etc.
I've had cortisol (abnormal) and epinephrine tests, but never the low-dose dexamethasone suppression test.
I think it's important that I take spironolactone as a diuretic, which affects the hormone adrenal aldosterone. It's not uncommon for aldosterone levels to be elevated when one has adrenal adenomas, but for some reason, neither my endo nor my pcp ever thought to remove me from the spironolactone and test aldosterone levels.
As for the Hashimoto's flare, right now, I'm putting my money on the high cortisol, nutrient deficiencies and out of balance gut bacteria... After having been wheat free for over a week, we went to an Italian restaurant for lunch today and I ate pasta and bread that I haven't been eating...Before I was even finished eating, I was burping and belching something awful and this evening, I feel like a bloated whale that's been washed ashore!!!
We'll see what comes of further testing, which was sent off yesterday.
How can doctors say unspecified hypothyroidism with thyroid antibodies! smh.
I have a very large hump on the back of my neck and had a few tests done to rule out Cushing's (24 hour urine test and low-dose dexamethasone suppression test) but it turns out that lump is from chronic insulin resistance.
You might have Subclinicial Cushing's (SC) though which means you can show some degree of hypercortisolism without typical signs or symptoms of overt Cushing syndrome. It's not as easy to diagnose as overt Cushing's disease but I did read 75% of SC cases are diagnosed with the overnight 1 mg dexamethasone suppression test. Symptoms commonly mentioned with SC are high blood pressure, obesity and impaired glucose metabolism.
I have a very large hump on the back of my neck and had a few tests done to rule out Cushing's (24 hour urine test and low-dose dexamethasone suppression test) but it turns out that lump is from chronic insulin resistance.
You might have Subclinicial Cushing's (SC) though which means you can show some degree of hypercortisolism without typical signs or symptoms of overt Cushing syndrome. It's not as easy to diagnose as overt Cushing's disease but I did read 75% of SC cases are diagnosed with the overnight 1 mg dexamethasone suppression test. Symptoms commonly mentioned with SC are high blood pressure, obesity and impaired glucose metabolism.
COMMUNITY LEADER
I, too, wondered about the "unspecified hypothyroidism" with elevated antibodies, but that's what they classified it as...then in another place, the same doctor said "primary hypothyroidism", which is Hashimoto's - so we have to wonder what his real diagnosis would be, don't we??
He had also put "unspecified vitamin B-12 deficiency" instead of Pernicious Anemia in one place, but specified Pernicious Anemia in the other place, so it would seem that he's a bit undecided... lol
I've read about subclinical Cushings, but again, doctors have never been willing do the dexamethasone suppression test (or the 24 hr urine test).
I do have the three symptoms you mentioned (high blood pressure, impaired glucose metabolism and weight issues), though, for the past few years, I've managed to keep my weight below the obese level - with great difficulty, though I'd never had weight issues prior to becoming hypo/Hashi's.
He had also put "unspecified vitamin B-12 deficiency" instead of Pernicious Anemia in one place, but specified Pernicious Anemia in the other place, so it would seem that he's a bit undecided... lol
I've read about subclinical Cushings, but again, doctors have never been willing do the dexamethasone suppression test (or the 24 hr urine test).
I do have the three symptoms you mentioned (high blood pressure, impaired glucose metabolism and weight issues), though, for the past few years, I've managed to keep my weight below the obese level - with great difficulty, though I'd never had weight issues prior to becoming hypo/Hashi's.
You might want to see an endocrinologist to run a few tests for subclinical Cushings. I found a couple of articles/studies which are far too long lol but I posted some of the info which is interesting.
"The authors reviewed records of 24 patients who underwent adrenalectomy for adrenal corticosteroid hypersecretion. They identified nine patients who had subclinical Cushing's syndrome (defined as patients with an adrenal incidentaloma and median serum cortisol of 2.0 µg/dL after 1 mg overnight dexamethasone suppression testing rather than the traditional cutoff of 5.0 µg/dL)."
"The median preoperative BMI was 33 kg/m2. Eight patients had hypertension and three had type 2 diabetes.
The median adrenal mass diameter as measured by CT was 3.1 cm.
Seven patients lost weight postoperatively with an average decrease in BMI of 2 kg/m2. One patient became normotensive and three patients were able to reduce antihypertensive medication."
Surgery May Improve Symptoms in Subclinical Cushing's Syndrome. by Peggy Peck, Executive Editor, MedPage Today
***
"The high prevalence of hypertension and metabolic disorders in patients with subclinical CS suggests that the clinically silent hypercortisolism is probably not completely asymptomatic. Variable extent and duration of subtle cortisol autonomous secretion may influence the clinical features. This hypothesis is supported by the fact that hormonal and clinical features improved in all patients after surgical treatment. This improvement, described also by other authors (9), was persistent during the follow-up period, even after resolution of the biochemical adrenal insufficiency."
Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma: Clinical and Biochemical Features _ The Journal of Clinical Endocrinology & Metabolism, Volume 85, Issue 4, 1 April 2000, Pages 1440–1448,
"The authors reviewed records of 24 patients who underwent adrenalectomy for adrenal corticosteroid hypersecretion. They identified nine patients who had subclinical Cushing's syndrome (defined as patients with an adrenal incidentaloma and median serum cortisol of 2.0 µg/dL after 1 mg overnight dexamethasone suppression testing rather than the traditional cutoff of 5.0 µg/dL)."
"The median preoperative BMI was 33 kg/m2. Eight patients had hypertension and three had type 2 diabetes.
The median adrenal mass diameter as measured by CT was 3.1 cm.
Seven patients lost weight postoperatively with an average decrease in BMI of 2 kg/m2. One patient became normotensive and three patients were able to reduce antihypertensive medication."
Surgery May Improve Symptoms in Subclinical Cushing's Syndrome. by Peggy Peck, Executive Editor, MedPage Today
***
"The high prevalence of hypertension and metabolic disorders in patients with subclinical CS suggests that the clinically silent hypercortisolism is probably not completely asymptomatic. Variable extent and duration of subtle cortisol autonomous secretion may influence the clinical features. This hypothesis is supported by the fact that hormonal and clinical features improved in all patients after surgical treatment. This improvement, described also by other authors (9), was persistent during the follow-up period, even after resolution of the biochemical adrenal insufficiency."
Subclinical Cushing’s Syndrome in Patients with Adrenal Incidentaloma: Clinical and Biochemical Features _ The Journal of Clinical Endocrinology & Metabolism, Volume 85, Issue 4, 1 April 2000, Pages 1440–1448,
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Would you be surprised if I told you I had an endo in charge of treating my adrenal adenomas? She ordered 2 consecutive cortisol saliva tests, which both came back showing that I produced no cortisol, whatsoever, at that time of day, and a blood metanephrine and normetanephrine test, which were both within normal ranges... She decided that I did not have pheochromocytoma and pronounced me "fine"... She, apparently, saw no reason to order the Dexamethasone suppression test.
Not once has Cushings or sub-clinical Cushings, been suggested or thought of. For the most part, until I went to the NP, my problems have mostly been thought to be my own fault...
Interesting to note: My doctor's office posted the results of the blood draw I had done last week, on their portal, so I got to see them ahead of my visit this morning... In June, when I had blood work, my cholesterol and triglycerides were both over range, as was my blood glucose level. This time, both, cholesterol and triglycerides were back to well within range and blood glucose was only 1 point over range.
The only thing I've changed since June was eliminating wheat, dairy and as much sugar as I can from my diet (I don't eat soy and very little processed foods)...
My thyroid levels have remained almost the same as they were in June. The only thing that changed was Free T4, which was 1.3 (0.8-1.8) in June and September just prior to changing my diet, but is now, 1.4 (same range); Free T3 is 3.2 (2.3-4.2) on both tests, with suppressed TSH.
In addition, Chloride levels are high and protein and globulin levels are low. The high chloride could indicate dehydration, since I was fasting; however, the low protein and globulin may indicate malabsorption. It will be interesting to see the NP at the end of the month and find out the results of the stool test I did.
I'm wondering if absorption issues may have been affecting my thyroid med, but the fact that my FT3 isn't changing might still suggest impaired conversion.
Not once has Cushings or sub-clinical Cushings, been suggested or thought of. For the most part, until I went to the NP, my problems have mostly been thought to be my own fault...
Interesting to note: My doctor's office posted the results of the blood draw I had done last week, on their portal, so I got to see them ahead of my visit this morning... In June, when I had blood work, my cholesterol and triglycerides were both over range, as was my blood glucose level. This time, both, cholesterol and triglycerides were back to well within range and blood glucose was only 1 point over range.
The only thing I've changed since June was eliminating wheat, dairy and as much sugar as I can from my diet (I don't eat soy and very little processed foods)...
My thyroid levels have remained almost the same as they were in June. The only thing that changed was Free T4, which was 1.3 (0.8-1.8) in June and September just prior to changing my diet, but is now, 1.4 (same range); Free T3 is 3.2 (2.3-4.2) on both tests, with suppressed TSH.
In addition, Chloride levels are high and protein and globulin levels are low. The high chloride could indicate dehydration, since I was fasting; however, the low protein and globulin may indicate malabsorption. It will be interesting to see the NP at the end of the month and find out the results of the stool test I did.
I'm wondering if absorption issues may have been affecting my thyroid med, but the fact that my FT3 isn't changing might still suggest impaired conversion.
I'd like to say I'm surprised but I'm not sad to say. I did find a bit of info that is interesting. Dr Kaslow lists "Hormone Imbalances that favor breakdown of tissue" as one of the causes of low total protein.
"A prolonged high blood concentration of cortisol in the blood results in a net loss of tissue proteins and higher levels of blood glucose."
- Precise Nutrition - All About Cortisol
**
"An increased level of blood chloride (called hyperchloremia) usually indicates dehydration, but can also occur with other problems that cause high blood sodium, such as Cushing syndrome or kidney disease."
- Chloride Labtest Online
**
"1. Cortisol decreases TSH, lowering thyroid hormone production.
2. Cortisol inhibits the conversion of T4 to active T3, and increases the conversion of T4 to reverse T3."
- Cortisol and Thyroid Hormones
"A prolonged high blood concentration of cortisol in the blood results in a net loss of tissue proteins and higher levels of blood glucose."
- Precise Nutrition - All About Cortisol
**
"An increased level of blood chloride (called hyperchloremia) usually indicates dehydration, but can also occur with other problems that cause high blood sodium, such as Cushing syndrome or kidney disease."
- Chloride Labtest Online
**
"1. Cortisol decreases TSH, lowering thyroid hormone production.
2. Cortisol inhibits the conversion of T4 to active T3, and increases the conversion of T4 to reverse T3."
- Cortisol and Thyroid Hormones
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