how long does 50mg of tramadol stay in your system

[cleite27]

one 50mg pill of tramadol takes how long to leave the system?

[dominosarah]

Why are you asking?

[killerzoey]

Oh, I forgot. Here's my source for that last quote:

http://www.benzosupport.org/drug_half-life.htm

Hope that helps

-Zoey

[killerzoey]

From what I've read, 6-7 hours is the half life in most people.

From http://www.opioids.com/tramadol/prescribe.html

"The plasma half-life of tramadol following a single and multiple dosing was 6 and 7 hours, respectively. This increase in half-life upon multiple dosing is not considered to be clinically significant or to warrant dosage adjustment for chronic use."

I've also read that 5x the half life takes you to a level that's deemed insignificant.

From Basic Clinical Pharmacology by Michael Winter:

"The time required for a drug concentration to reach steady state is determined by the drug's half-life. It takes one half-life to reach 50%, 2 half-lives to reach 75%, 3 half-lives to reach 87.5%, 3.3 half-lives to reach 90%, and 4 half-lives to reach 93.75% of steady state....In most clinical situations, the attainment of steady state can be assumed after 3-5 half-lives."

[overopiates]

What do u mean?How long before it no longer give pain relief or how long before its out of ur system as in undetected?