Hello all. I haven't been on here for quite sometime. I guess I was feeling fine for that time. But now for the last 3 weeks I feel so crappy' no energy, negative thinking, muscle twitching, hard to breathe at times and a general lousy feeling. I am still on medication Clonezapam and clomipramine. I have tried to taking double my regular dosage but it seems to have no effect. The dosage I am taking is 100mg Clomipramine 1mg Clonezepam . I have question is it possible foe medication to stop working as I have been on this combination for 19 years now. Thank you all in advance who can respond to my question.