I have been on Zoloft for about 7 months now, after dealing with crippling anxiety and depression. this medicine really worked wonders! recently I was put on Minocycline for my chronic forehead and shoulder acne, and I was all for the idea of clear skin, whether I had to take pills or not. ever since, slowly but surely, my anxiety is making a reappearance, along with my depression, both of which I thought were long gone. I am unable to function properly at school, ride in the car, watch TV, or even sit on the couch doing nothing without having anxious thoughts running through my mind! I'm not enjoying my life, and I never thought I would have to deal with this again! I don't know whether the Minocycline is causing this, or if I'm experiencing SSRI poop out, but either way, I need help!! I feel crazy and I have an appointment with my physician for a physical and hopefully blood work scheduled for next week, but I'm scared he won't be able to tell me what's wrong or help me! a side note, I feel as though this could possibly be Hypothyroidism, as I have been extremely tired and moody over the past month or so, which is longer than I've been on Minocycline. I don't know what to do. HELP!!!!!!