My question is, can someone tell me when is the best time of the day to take wellbutrin 100mg once a day. Right now i take it about 6;30 pm every day and i can't seem to sleep. Could this be the problem. Maybe i need to take it in the morning. I also take xanax .05 one a day. This is suppose to be for menopausal anxiety. Can anyone answer this question, I need to sleep. THANKS