autoimmune disease but which one

[cleasho]

In the past 6 months my health has went down hill.  Started with big toe on left foot going black, then right, now both feet are changing colour and cold like the weather,(hands are same).  Diagnosed with Raynauds, then Livido Rectularis set in legs, arms, hands and torso. Severe pain in all quadrants of the body.  Feel so tired all the time can sleep 15hrs a day no problem.  Hand tremors started and this can be severe sometimes feel in legs as well as though whole body shaking.  Low B12 and folic acid and slightly raised coeliac test (had biopsy last week and awaiting results).  I now think i may have sciatica as the pain in lower back and legs is causing me to sop in my tracks. i also have fast heart rate and high blood pressure again all started 6 months ago taking medication for these.  feel sickly alot and getting depressed, i just want my lif back.
Have you got any ideas.  rhuemy thinks may have fibromyalgia. Been tested for lupus twice but results negative

[pinkladypain]

Sounds like Raynauds, the toes going black tho, sounds like Buerger's Disease (a vascular disease) caused by smoking.  I was diagnosed with it about a month ago, after endless trips to er for pain, but it has taken them this long to diagnos, and still have 1 more test the angiogram.  Should have been done uin the beginning, now th;ey will be amputating my middle finger.

[cleasho]

thanks for your comments and i will certainly be looking into these condtions.

[Red_Star]

Symptoms of B12 deficiency include tremors, extreme fatigue, sciatic nerve pain, tachycardia, depression.  A B12 deficiency has been noted to cause high blood pressure in some patients however more commonly causes low blood pressure.

The most common nutritional deficiencies in people with celiac disease include essential fatty acids, iron, vitamin D, vitamin K, calcium, magnesium, vitamin B12, and folic acid. Magnesium deficiency causes tremors, high blood pressure, fatigue, depression, mimics fibromyalgia. Interesting to note is magnesium deficiency is associated with secondary Raynauds.  Vitamin D deficiency symptoms include bone and muscle pain, depression, fatigue, high blood pressure, and also mimic fibromyalgia.

A highly significant association exists between celiac disease and autoimmune thyroiditis (Graves' disease and Hashimoto's Thyroiditis). Grave's disease is autoimmune hyperthyroidism and Hashimoto's Thyroiditis is autoimmune hypothyroidism. Tremors, fatigue, fast heart rate are some of the symptoms of Grave's disease.  Hashimoto's Thyroiditis does swing between hyper and hypo symptoms and also mimics fibromyalgia.

Primary Raynaud's - without an underlying disease or associated medical problem.

Secondary Raynaud's has a number of associations:

Connective tissue disorders:
Scleroderma
Systemic lupus erythematosus
Rheumatoid arthritis
Sjögren's syndrome
Dermatomyositis
Polymyositis
Mixed connective tissue disease
Cold agglutinin disease
Ehlers-Danlos Syndrome

Eating disorders:
anorexia nervosa

Obstructive disorders:
Atherosclerosis
Buerger's disease
Takayasu's arteritis
Subclavian aneurysms
Thoracic outlet syndrome

Drugs:
Beta-blockers
cytotoxic drugs - particularly chemotherapeutics and most especially bleomycin
ciclosporin
ergotamine
sulfasalazine
anthrax vaccines
Antigen

Occupation:
jobs involving vibration, particularly drilling, suffer from vibration white finger
exposure to vinyl chloride, mercury
exposure to the cold (e.g. by working as a frozen food packer)

Others:
Physical trauma
Traumatic events
Hypothyroidism (most common cause is Hashimoto's Thyroiditis)
Cryoglobulinemia
Malignancy
Reflex sympathetic dystrophy
Carpal tunnel syndrome
Magnesium deficiency
Erythromelalgia

A number of conditions may cause the appearance of livedo reticularis:

Cutis marmorata telangiectatica (rare congenital condition)
Sneddon syndrome
Idiopathic livedo reticularis (unknown cause)

Secondary livedo reticularis:

Vasculitis autoimmune conditions:
Livedoid vasculitis
Polyarteritis nodosa
Systemic lupus erythematosus
Dermatomyositis
Rheumatoid arthritis
Lymphoma
Pancreatitis
Tuberculosis
Amantadine (drug)

Obstruction of capillaries:
Cryoglobulinaemia
Antiphospholipid syndrome
Hypercalcaemia (high calcium levels)
Polycythaemia rubra vera
Thrombocytosis
Infections (syphilis, tuberculosis, lyme disease)
Acute Renal Failure
Arteriosclerosis
Homocystinuria
Intra-arterial injection

Ehlers-Danlos Syndrome