Any advice on a complicated situation?

[anonymous228]

I have been TTC for three years and struggle with recurrent miscarriage. I am 23 years old, short, and thin (just about 100 lbs.). I have had tons and tons of bloodwork. All comes back normal except I have low estrogen (Day 3= less than 20) and low progesterone (Day 22= 8.4) issues.  I have a borderline high FSH level (8.9).  I do have pretty bad acne, though it is significantly worse toward the end of the month.  My husband has had everything checked and everything has come back great.  I characteristically have had no issues getting pregnant. We have had 5 miscarriages; none were checked for chromosomal errors.  They were:

1. 6 weeks, miscarried naturally
2. 12 weeks, blighted ovum, D&C
3. 5 weeks, chemical miscarriage, miscarried naturally
4. 5 weeks, chemical miscarriage, miscarried naturally
5. (after first try at Femara) 7 weeks, heartbeat detected, normal morphology, had to take Misoprostol to induce miscarriage.

My doctor gave me the choice this next time of whether I wanted to use progesterone cream as a supplement, but he said in his opinion I did not need it.  I used it along with Femara, did not conceive, and felt horrible the entire second half of the month.  I was exhausted, my breasts stung, and I was in a horrible mood.  Previous to using progesterone cream I have never had a PMS symptom in my life.  This month I decided not to use the progesterone cream but continued the Femara.  I felt sure that I would get a positive test because I felt even worse than last month, but sure enough I got a negative pregnancy test and my period came.  So, whereas I used to have no trouble getting pregnant and no PMS symptoms at all, all of the sudden it seems I cannot get pregnant and have developed severe PMS.  I know I have been ovulating due to ultrasounds.  Any ideas?

[anonymous228]

I have had my TSH, T4s and T3s tested this year and last.  All came out normal both times.  However, my mother has Grave's Disease, so I will continue to get it checked every year probably to catch it when it starts to change (if it does).

[Surprise5]

Change ur doctor . Maybe he's missing something .

[naan84]

I'm sorry for your loss, its so difficult when you feel your doctor has given up, I've just changed mine as we were getting nowhere.
Have you had your thyroid tested? After trying for 12 months I found out I had a thyroid problem, we got it under control in 3 months and I conceived (unfortunately miscarried) but now I know I have to watch my thyroid levels. Your thyroid, if out of balance, can either cause you to not ovulate or if you get pregnant can cause a miscarriage if levels get too high, might be worth testing, its a blood test.

[anonymous228]

I've been working with him for a year and a half and each time something looked successful he told me that progesterone is just a last resort to give me the feeling that I have some control over things, but like I said, told me in his opinion I didn't even need it.  He called the use of it "strictly a personal choice."

[Swtshae]

What else does your doctor suggest? There has to be a reason you're having continuous miscarriages. I'm sure your bloodwork results has a lot to do with it. Also, they should be making recommendations as to what they think will get you with a healthy pregnancy.