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4th Generation Elisa antigen/antibody test

Hi all

Is it right that this test will give conclusive result after 28 days+ exposure to HIV as per the medhelps HIV preventions international forum, I belive the doctors are from the UK.  They seem pretty sure of this and seem to be moving to a 6 week window period as per Australias current testing policy.  
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Avatar universal
The UK is just like the US in the testing guidelines 3 months is conclusive.  
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Avatar universal
Thanks for those guidelines Teak, I have studied and agree that the UK still suggest testing at 6 months to be sure of conclusive testing, however doctors at private clinincs who have been testing on the 4th generation AG and AB test in the UK are claiming that after ten of thousands of these tests they do suggest that a 28+ 4th generation test is conclusive as per Australias guidelines.  I suggest the UK are been overcautious and protecting against any false negatives, although these are next to non exsistent.  Your thoughts please...
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188761 tn?1584567620
COMMUNITY LEADER
AG = P24 in this reference.
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188761 tn?1584567620
COMMUNITY LEADER
Agreed! The detectable AG window is 21 - 28 days post exposure.
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Avatar universal
the antigen is at a peak
at  around 21days, for an infected person,hence the guidelines of a 6 week in australia.  
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Avatar universal
the antigen is at a peak
at  around 21days, for an infected person,hence the guidelines of a 6 week in australia.  
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188761 tn?1584567620
COMMUNITY LEADER
Actually, per Aus testing guidelines, it is correct that a conclusive test result could be attained with a 6 week negative.

Why? The australian DOH has approved the 4th gen AG and AB test long while back and people are tested on 3rd and 4th gen test.

I have personally once spoken to the Sexual health information line run through Sydney Sexual Health Clinic, they told me they recomended testing at 6 weeks for conclusive result.

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Avatar universal
No that is not true. Here is the UK testing guidelines.

http://www.bhiva.org/files/file1031097.pdf
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Avatar universal
no risk, just extremely interested in different countries views on when a "conclusive" result is given. I'm from UK and it seems that the DUO test is most recognised ELISA test and they seem to suggest 28+ day test is conclusive and only reason 3 month test is requested is to cover the medical bodies.  IN your experience how many people who test neg at 6 weeks on DUO test then go onto test positive at 3 months??
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480448 tn?1426948538
Currently, no test is approved to give conclusive results before 3 months.  Until the official guidelines change, that is what we recommend on this forum.  A Neg result at 6+ weeks is a very good indication of your final result, but not conclusive.

What was your "risk" anyway?
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