this is the old study we already know about, the new one should be in asia, dont remember if india.those sides effect might be prevented by use of high dose vit b12, hopefully they ll use it in the next study
http://cat.inist.fr/?aModele=afficheN&cpsidt=2917475
https://clinicaltrials.gov/show/NCT02288208
It says the study is terminated due to cranial nerve palsies on Sep 09, 2015.
I am disappointed to read some members tried ntz tdf and IFN combo for 1year but still can't clear the b virus
The Birinapant HBV clinical trial is on-going, but is not recruiting. The public has not been told how many patients still remained in the trial and whether anything has changed - a wall of silence.
Sure you can buy Birinapant, but it is for research use only. Why would anyone try it if it hasnot yet been proven safe or effective? Also, it has not been approved as a drug for cancer, it is still in Phase 2.
& i remember studyforhope said the bell's pelsy just needs two weeks for the full recovery so my assumption is to wait some data from them as scheduled.
Hope they'll surprise us with some thing since they are not on hold by FDA just tetra stopped the trial from more disaster.
I thought birinapant is currently on hold as it caused issues during trials
study will finish soon so hope they will publish some update
https://clinicaltrials.gov/ct2/show/NCT02288208?term=birinapant&rank=2
I am asking this because it might already b available as cancer curing agent
Is birinapant commercially available and is it advisable to take it despite the palsy it causes.
I can see it available here
http://www.molbase.com/en/search.html?search_keyword=birinapant&gclid=CjwKEAjw5J6sBRDp3ty_17KZyWsSJABgp-Oaax-4mad86DDgQqD-pebYC9MjBobpTX1aZ-1Aa5Y-0xoCGHPw_wcB
Are there any news about birinapant?
That was the first think came to my mind, they might probably got a huge money from the some big pharma, hope the almighty God see our humbleness.
It is sad that everytime we get a little hope on a cure some other things come up. Hope they not just playing games with us
Yes i hope as i read also that bell palsy can be cure using another drugs... maybe it can be added as compound
Be optimistic sure scientists know that the trial will face some dangerous side effects and sure they are working on and how resolve these problems.hope they will continue and find solutions.
I'm so sad after hear this news. No longer any hope for deleting HBV out the body? F**k HBV :(
Oh my. Looks like the hope for Binirpant has quickly turned around. I wonder if there's a condition this person had which triggered this side effect.
We can't wait for full recovery in two weeks & proceed with their trials. Finger crossed!!!!
it is hard to predict how the fda will react. the recovery process from the palsy and speed will also determine that. it should only take 2 weeks to recover, but i dont know if they will use methylcobalamine to speed up recovery.
Good to know. This initially worried me as I do know someone that got Bell's out of the blue and is still completely debilitated for over 2 years now, without much improvement and tons of therapy.
Do you think they will restart the trial if others want to go forward, or do you think the FDA will shut it down? You are very knowledgeable and I am very new to the background of how trials function. I was really hoping for great news from this one, as I know we all were. Let's just hope it's not a complete wash.
thanks man !! the part hope in your nickname is well deserved, study as well btw :)
The Bell's palsy caused by BIRINAPANT is not the same as regular spontaneous Bell's palsy. It will typically disappear fast upon discontinuation of the drug. Methyl cobalamin injections will speed up recovery and might possibly have preventative effects. However i doubt that the situation is handled this way.
We do not know at which dose level and what frequency this problem occurred. One can only hope that the trial will continue after it has cleared up.