Celgosivir

[susan400]

When I was googling, trying to find out different reports from the EASL, I came across the reports about this new drug that was being investigated for treatment of Hep C.  Apparently, in a small study, it showed a good response rate to the viral loads w/SOC, if I'm reading it correctly.  It looks like they're moving on to Phase II studies up in Canada for naive patients.  I'm hoping that it turns out well and that they come on down to the U.S.  I'm trying to watch out for something down the road besides Telaprevir, since I won't qualify for any of their next phases of trials.  I was turned down for any of the later trials coming up.  Which in my opinion is unfair, since I already allowed them to make me their G-pig and was randomized into Group C the no-Riba group.   I feel that they should allow us Prove 3/Group C people who (most of us were non-SVR), the opportunity to treat with all 3 drugs.  But, since they won't, I've got to 'keep my options open', which is what I've been told to do.  I was told to keep on investigating other trials and trial centers.  So, if any of you hear about anything else out there for me to look into, I'd certainly appreciate it.

Susan

[susan400]

I am putting in my own comment here, just to keep this thread active, a least for a few hours??  

Susan

[susan400]

My hepatologist has already asked the Vertex rep if I could participate in any of the later Telaprevir trials and I was told that I would not be a candidate.  The only hope is if they come back and let us from Prove 3-Group C have a rollover option, or wait until WHENEVER they finally get around to FDA approving it.  But, the problem with that is whether or not the insurance company is going to be willing to pay for it at that time.  

Susan

[foofighter]

Yes. I think my NP might have been saying just that. Are you sure that things haven't changed? I know they were concerned about resistance to telaprevir for you guys, but did that actually happen? I can't remember if there were actual studies that revealed that info.

Check out the info that toughluck just posted. All sorts of news.

[FrontRangeMom]

Once all the results are in for Prove 3 and the results are unblinded they might just do a rollover for Group 3.  Just speculating. I've heard that a telaprevir study for non-responders/relapsers (including cirhhotics with compensated disease)  may be started in the US later this year.  I'm hoping for that one myself, even though that one is also supposed to include a placebo controlled arm.