Hep C genotype 4

[peggy156]

Hello, what is the latest drug treatments being used for genotype 4 and any recommendations on the best place to seek treatment in the NYC area. Thanks very much


Peggy

[Bali05]

"fibroscan did show some fibrosis"

FibroScan is most reliable to determine early stages or late stages of fibrosis.
Not very reliable in the mid stages.If you are in the mid or late stages on
FS but still want to wait you should do biopsy.

Who did your FibroScan ?

Did they recommend to treat now based on your FS results or can you wait ?

Anybody who tells you they will tx geno 4 with Incevik does not know what they are
talking about.

1) It did not improve SVR in a small geno4 study but has additional side effects
2) It is not FDA approved for geno4 and costs approx. $48K for 12wks off label use.

[Boobert]

I truely doubt any insurance company will pay for Incivek for a Geno 4. There's no Clinical Data that it will even work on geno 4.

[peggy156]

should have said doctors up here have not had experience with g 4

[peggy156]

Thank you all for your replies. I do not know my subtype yet, fibroscan did show some fibrosis. The gastro docs up here in upstate NY say they would treat me with the pega interferon ,rivarin and incivek but all have said there is experience with gentype 4. I have tried to get in touch with Dr Dietrich and Dr Talal at Wein Cornell- so far no replies. I will keep trying.

[Bali05]

Hi Peggy,
I am also Geno 4 and loacted in NYC.
Hepatologists that were recommended to me are:
Dr. Ira Jacobson , Dr. Douglas Dietrich , Dr. Hillel Tobias

I assume you are tx naive so I would try and do 2 things first:

1) Get an idea if  you have any fibrosis (Biopsy,FibroScan,FibroSure,Bloodwork)
2) Run the IL28b test

If you decide to tx right now I would add Alina (Nitazoxanide) to SOC.
You can google it  (Nitazoxanide genotype 4).

Do you know your geno 4 subtype ?

For example I am (hopefully was)  4 a,c.

It appears that 4a is easier to tx than geno 4s.

b

[Boobert]

Hi Peggy,
I am also a Geno 4 and I hate to tell you but there isnt anything NEW availiable for us yet. Unfortunately there just isnt enough of us 4's in the US to be profitable for the drug companys to research. Bali definetiley knows his stuff on our type and I am sure he'll be posting soon about how he has conquered this virus. There are new drugs in trials right now but atleast a few years away. You still have SOC treatment which is around 60% sucsessful for us Geno 4's.Welcome to the forum.

Bob.