Started GS 7977 & Ribavirin Trial

[HectorSF]

Hi all!

I started my HCV clinical trial treatment yesterday.

'An Open-Label Study to Explore the Clinical Efficacy of GS 7977 With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant'
NCT01559844

Primary Outcome Measures:
Determination of post-transplant virological response [ Time Frame: 36 Weeks ] [ Designated as safety issue: No ]
To determine if the administration of a combination of GS 7977 and ribavirin to HCV-infected subjects with hepatocellular carcinoma (HCC) meeting the MILAN criteria prior to undergoing liver transplantation for up to 24 weeks can prevent post-transplant re-infection as determined by a sustained post-transplant virological response (HCV RNA <LLoQ) at 12 weeks post-transplant.

Treatment Drugs:

2 200 mg of GS-7977 in morning
3 200 mg of Ribavirin in morning
3 200 mg of Ribavirin at night (12 hours later)


But I am now on treatment and will continue for 24 weeks or transplant, which ever comes first.

I stopped my TB treatment today. I will deal with TB after transplant.
I just had a cancer screen MRI/AFP and I am waiting for the results...

I can't believe that within 4 weeks I will have no viral load for the first time in 42 years!!! Once I become undetectable I will be looking for a transplant. This treatment is my best shot at curing my hepatitis C as a previous null-responder.

I heard through the grapevine that a trial with GS-7977 will be starting for post-transplant patients who are infected with hepatitis C. The cure rate now is only 30% using peg-interferon and ribavirin. Very poor results so we need more options.

Happy- :-))
Hector

[OC]

good luck brother, hope it works for you!

peace

[FaithforHealing]

Thinking of you and hoping for the best! We will all be following you. I guess this thread may be the HectorSF thread so we don't miss any updates?
You have helped so many....it's your turn to reap the rewards!

[jsf52]

You have helped so many people in their struggle - it is exciting to see you have this incredible opportunity for a cure and a bright future.  You are an inspiration to all of us.  I look forward to seeing the UND post soon.  Will keep you in thoughts and prayers.  

[rexx73]

dear hector,

thats fantastic news.
i hope so much this will work for you and get rid of this virus before transplant.

best wishes
marc

[coeric]

Godspeed my friend,
eric

[UKgirl55]

Wow! I love your spirit and honestly, it's the only way to go, which I know you know. You're so right, in that you'll be paving the way for others :-) What a true blessing to have this trial come along when it did. There was obviously a plan in the works for your life :-))
Very, very happy for you Hector BIG (((hugs)))