Hi, is he still on the Bactrim? If he has finished the Bactrim and is having swelling, I would get him checked out. I guess if it was me, to be on the safe side, I would go back to the doctor either way.
Good luck
Dee
He needs to be checked for fluid retention and cirrhosis. Fluid retention ascites is a common issue with advanced hep c. The big thing, elevate, avoid salt and get checked. You can develop sepsis!