I woke up one morning in November of 09' with a headache. It is now April 1st of 2010, I still have a headache. At this time I was on Pravastatin for Cholesterol, I have been on this for about 2 years. I have been on Zoloft 100 mg for 15 yrs. I thought it was nothing didn't take anything thought it would go away, WRONG!. I have had migraines for probably 20 years. This is not a migraine. I have taken Tylenol, didn't work, took Advil, didn't work, took Ibuprofin, didn't work, so I went to the doctor. She ordered a cat scan put me on fioricet, didn't work, cat scan clean. Saw Neurologist. MRI done. Clean. Put me on Topamax. He is increasing my Topamax by one pill a week for 4 weeks so by the end of those 4 weeks I will be takinng 4 pills a day. No relief. He says they are rebound headaches. I doubt this. So he has one more week to figure this out because I am at the end of my rope. I need some advice PLEASE!