I have been suffering from a consistent migraine/headache for over seven months now, about since the time my thyroid began failing, it was found out that I have hashimotos disease. I am still trying to get the correct does of synthroid but even at .137 my T4 count was -10. I also have GERD, which I take nexium for, IBS which I occasionally will take either hyoscyamine or donnatal for, and I take xanax for anxiety and also because I am afraid around new people. I also have fibromyalgia for which I was entered into my states medical marijuana program. I was first tried on Topamax but I was not able to tolerate the medication. I had read about psilocybin/LSD for the treatment of cluster headaches. I have found that LSD relieves the severity of my migraines. After a dose of LSD I have 2-3 weeks where I only need verapamil and occasionally mild pain meds. After four or more weeks my migraines comeback full swing on a daily basis. Recently I have been taking 6 aspirin 1100 mg of naproxen sodium and several percocet on a daily basis on top of smoking MJ. Even with such a ridiculous amount of medication it only dulls the pain.
I understand that LSD and psilocybin (I have not tried for my headaches) are 5-ht agonists and that this class of medicine is commonly used to treat migraines. I believe that imitrex and other newer migraine medicines are NSAID's (I can barely tolerate the aleve and aspirin). I was wondering if perhaps ergotamine which I understand was commonly used in 1980's for migraine treatment might be a good substitute for using illicit substances. I do not feel comfortable speaking with my neurologist about my self medication because of the stigma attached to "drug use" and also I currently do not have a prescription for percocet either (I am afraid to ask because I don't want to be labeled as a seeker, even though he said I could go to the ER for shots). Any information would be great, where I live there is no one who specializes in migraines. I apologize for my bad grammer.