You might want to post on the addiction site as I believe you should get fairly good answers there. I don't know about mixing painkillers or any drugs unless doctor approved.
I know tramadol has some sort of anti depressant properties and can be a bear to get off of from what I have read.
Tramadol is not in the same family. It is not considered an opiate. It does have similar actions and it is my guess it will soon be reclassified. It has NO antidepressant properties. It is prescribe for pain.
The others are all opiates. Why would you ask?
Sorry, I was incorrect on the tramadol having anti depressant properties.
I should not have posted on a drug I really don't understand. I'm glad Tuckamore caught my mistake.