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Dear Walter
I am not personally aware of any reported interaction with amiodarone and mefloquine. However, I have not prescribed that combination myself. Check with the doctor that prescribed the mefloquine.
I hope this has been useful. I wish you the best of luck. Feel free to write back.
If you would like to make an appointment at the Cleveland Clinic Heart Center, please call 1-800-CCF-CARE or inquire online by using the Heart Center website at www.ccf.org/heartcenter. The Heart Center website contains a directory of the cardiology staff that can be used to select the physician best suited to address your cardiac problem.