The condition of your aorta and aortic root is unrelated to the use of those medications. BAsed on what you described above, you will need valve surgery soon. I think it's ok for you to use the nasonex and the allegra. I would not use the afrin. It's not safe in patients without any heart disease if used longer than 3 days anyways. It may actually make your condition worse due to a rebound phenomenon that frequently occurs with this medication.