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Decongestants and heart valve disease
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Decongestants and heart valve disease

Can the prolonged use (5 and a half years) of Nasonex, Afrin nasal spray, and Allegra D or the same family of drugs cause damage to the heart valves, if on already had a preexisting problem ?  

I am 38 and was diagnosed with mild aortic regurgitation 18 years ago.  The problem remained mild for 13 years and I was told 5 years ago to have an echocardiogram every 5 years.  

Five years ago I also hurt my nose playing basketball.  Fearing the corrective surgery to fix my deviated nasal septum, I have taken the above mentioned decongestants for five years.  My recent echocardiogram demonstrated severe aortic regurgitation, thickened intraventricular wall, dilated left ventricle, dilated aorta etc.

I have not had high blood pressure over this time.

Please advise.
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The condition of your aorta and aortic root is unrelated to the use of those medications.  BAsed on what you described above, you will need valve surgery soon.  I think it's ok for you to use the nasonex and the allegra.  I would not use the afrin.  It's not safe in patients without any heart disease if used longer than 3 days anyways.  It may actually make your condition worse due to a rebound phenomenon that frequently occurs with this medication.  
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