INR values

Posted by Catherine RN on May 07, 1999 at 13:24:09
Please explain the meaning of INR lab results in relation to PT lab results.  Alos can the effects of coumadin therapy for deep vein thrombosis be affected by either SIADH or hypothyroidism?  Both of these conditions exist due to (I think) chronic use of DVPA and carbamazipine in a severly mental retarded female who has frequent seizures.  Thanks for your help!

Posted by CCF CARDIO MD - DLB on May 09, 1999 at 20:02:42
Dear Catherine
Both the INR and PT are measures of blood anticoagulation. The INR is the more accurate and modern method of measurement. There is no way to convert between the two values.
The medicines she is taking can interfere with the effect of coumadin. Therefore, the INR just needs to be monitored closely, especially with any dosage changes, and kept in a therapeutic range.
I hope this has been useful. Feel free to write back with further questions. Good luck.
Information provided here is of a general nature.  Specific diagnoses and treatments can only be made by your doctor.  If you would like to be seen at the Cleveland Clinic, please call 1-800-CCF-CARE for an appointment with a cardiologist at Desk F15.