GS-7977 and Ribavirin Clinical Trial

[HectorSF]

I found out today I AM UNDETECTABLE after 2 weeks of treatment with GS-7977 and Ribavirin.

Not bad for a previous null-responder to peg-INF and Ribavirin where after 12 weeks of treatment my viral load never went below 360,000.

"An Open-Label Study to Explore the Clinical Efficacy of GS 7977 With Ribavirin Administered Pre-Transplant in Preventing Hepatitis C Virus (HCV) Recurrence Post-Transplant"  ClinicalTrials.gov Identifier: NCT01559844

During screening my viral load was 1,200,000
On day 1                                         692,000
1 week                                                   581
2 week                                                   <25

COBAS TaqMan HCV Test
week 1 dropped 3.06 logs
week 2 dropped 4.44 logs

Cheers!
Happy
Hector

[creewoman]

There are rare human beings that persevere against all odds and come out as victors.I have not been on the forum long,but it is obvious you are one of the blessed ones going on for all too sick to make it and for the rest of us just beginning the journey a Pioneer.Thank you.I curtsy to you!
  Snow

[jojim55]

Congrats Hector

[gerard11]

Very happy to hear your transplant went so well. I too was out of the  hospital after 5 days!!! I find that amazing, to have that surgery and spend such a short time in hospital. Hope you remain Hep free. Hope all is well with bone marrow tests. You have been thru the mill and its time for you to mend and get your life back!!!!! Congrats on your gift of life!!!!!!!!!!!!!speedy recovery!

[revenrick]

i was transplanted dec 30,2012.only spent 5 days in hospital,all levels look good,i go to clinic twice a week,they 2x my prograf since start,some blood markers from old liver show  some lymphoma of unknown type waiting for bone marrow test to find out more will update later, hector are you out there?

[fran4702]

Congratulations Hector!  You have been so kind to everyone on this forum.

[libnic84]

that my friend has to be one of the best feelings in the world... congrats!!!  i'm so excited for you

[revenrick]

i really had no  side effects with gs7977,normal side effects with riba ,like rash and itching,having took interferon three different  times with riba ,48 weeks each time ,over a ten year period,only to relapse each time around the six months checkup.......,the gs7977 was an open label trial,took two  200 mg each day, 400 mg total a day with riba,1200mg a little dizzy at times,but nothing like what i went thru with the  interferon,the only negative thing of gs7977 was the taste ,taste like sulfur,ill take that over interferon any day

[MeWithC]

Glad it worked for you Hector....maybe my turn will come soon.

[gerard11]

How was your treatment on the GS-7977 / RIBA ?  Side effects? If you could talk about the experience I am sure many members would appreciate it. I know I would be one. Thank you...and good luck on your upcoming transplant. I

[revenrick]

congrats hector, i my self just finished 24 weeks of gs7977 and riba,and awaiting tx ,im a type3 null responder 3 times ,over last 10 years..my viral load started at 300.000 by week 3 it was >25 undetectable ,i just moved up to #2 on tx list ,have had 3 calls for backup transplant,over last two weeks,my meld score is 25 should go to 28 next week,looks like ill have a rebirthday with a new year .... from here in texas   good luck  hectorsf     !!!!!!!!!

[LookingForward12]

I may be late to the party, but heartfelt congrats are here for you now!

You are, undoubtedly, one of the most brave and stickwithit people on this forum. When you are ready, let me know, I'll send you a bushel of onions for that new liver!

Cheers!

[GINGERPAL]

Hector....This is wonderful news.  I wish you all the best !!  You deserve it.  gingerpal

[lapis]

REALLY late to this party but it continues!!!  Such fabulous news, I am so very happy for you, Hector.  Still cheering from the east coast!!

Lapis

[JDB1964]

Happy for you and so anxious for this great med to become available to all who need it!

[IAmTheWalrus]

Amazing! This is appropriate for such an amazing guy. This definitely makes my day!

[katla]

I don't come around here much and just came across this. I was delighted to read this, truly.

Wishing you the best of luck with this trial.

[gene53]

Like I always say, YOU ARE DA MAN.... Congratulations and very best of luck

[stormy456]

I had such a good feeling about this treatment for you, and here we are.  I'm so very very happy for you, H.  This is a significant milestone on your road to living a healthy, full life.  Wishing you a very easy remainder of tx.  - H

[child24angel]

Hector!!
This is WONDERFUL,!!!!

All my very best moving forward!!

Many Hugs
Elaine

[Dee1956]

Hey there!  Day late $ short Dee here to say congratulations!
I am so very happy for you, this is the best news!
Woo HOO!
Dee

[Revalation]

Wonderful news.
You deserve some good news.
Wishing you the best.

Reva

[flcyclist]

I almost missed this.  Just browsing through the post and see this wonderful news.  Hector UND @ 2 weeks!!!  Friggin fantabulous!!!!!!  What a wonderful way to start the day.  Puts a big smile on my face to hear our Hector is well on his way to SVR.  
☻ღ˚ •。* ♥ ˚ ˚✰˚ ˛★* 。 ღ˛° 。* °♥ ˚ • ★ *˚ .ღ 。~♥~
~♥~˛˚ღ •˚ ˚…just sprinkling a little Love on your page. ~♥~˚ ✰* ★
˚. ★ *˛ ˚♥* ✰。˚ ˚ღ。* ˛˚ ♥ 。✰˚* ˚ ★ღ☻~♥~* ♥ ˚ ˚✰˚  :-)))

[HectorSF]

¸¸.•*¨*•*´¨)
¸.•´¸.•*´¨) ¸.•*¨)
(¸.•´ (¸.•`  Thank you every one!!!

[JasmineT]

And there it is!  Great news hector!